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MSL2

male-specific lethal 2 homolog (Drosophila)

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.

Gene Name: male-specific lethal 2 homolog (Drosophila)
Synonyms: MSL2, KIAA1585, Male-specific lethal 2-like 1, MSL2-like 1, MSL2L1, RNF184, MSL-2, RING finger protein 184, Male-specific lethal 2 homolog
Target Sequences: NM_018133 NP_060603.2 Q9HCI7

☰ Filters
Antibodies (22)
Proteins (7)
Over-Expression Lysate (4)
Primary (22)
Recombinant (3)
MSL2 (29)
Human (22)
Mouse (4)
Rat (4)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
WB (21)
ELISA (6)
IP (1)
rabbit (14)
mouse (8)
IgG (13)
IgG1 (2)
IgG2a (6)
monoclonal mc (8)
polyclonal pc (14)
OTI3B11 (2)
OTI3G5 (2)
OTI4G7 (2)
OTI6C10 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (4)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (14)
aa4-32 (7)
N-Terminus (4)
No (29)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (4)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed
Select
MSL2 Mouse anti-Human Monoclonal (OTI3G5) Antibody
Human
WB
Unconjugated
100 µl/$434
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MSL2. (1:2000)
Select
MSL2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed
Select
MSL2 Mouse anti-Human Monoclonal (OTI6C10) Antibody
Human
WB
Unconjugated
100 µl/$434
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MSL2. (1:2000)
Select
MSL2 Mouse anti-Human Monoclonal (Carrier-free) (OTI6C10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed
Select
MSL2 Mouse anti-Human Monoclonal (OTI3B11) Antibody
Human
WB
Unconjugated
100 µl/$434
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MSL2. (1:2000)
Select
MSL2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3B11) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed
Select
MSL2 Mouse anti-Human Monoclonal (OTI4G7) Antibody
Human
WB
Unconjugated
100 µl/$434
MSL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MSL2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MSL2. (1:2000)
Select
MSL2 Mouse anti-Human Monoclonal (Carrier-free) (OTI4G7) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
MSL2 Antibody - MSL2 / MSL2L1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MSL2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
MSL2 Antibody - MSL2 / MSL2L1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MSL2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
MSL2 Antibody - MSL2 / MSL2L1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MSL2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
MSL2 Antibody - MSL2 / MSL2L1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MSL2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
MSL2 Antibody - Western blot analysis of extracts of various cell lines, using MSL2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
MSL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MSL2 Antibody - MSL2 Antibody western blot of CEM cell line lysates (35 ug/lane). The MSL2 antibody detected the MSL2 protein (arrow).
Select
MSL2 Rabbit anti-Human Polyclonal (aa4-32) Antibody
Human
WB
Unconjugated
400 µl/$393
MSL2 Antibody - Anti-MSL2 rabbit polyclonal antibody at 1:500 dilution. Lane A: 293T Whole Cell Lysate. Lane B: HeLa Whole Cell Lysate. Lane C: U-251 MG Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 62 kDa. Observed band size: 62 kDa.
Select
MSL2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
MSL2 Antibody - MSL2 was immunoprecipitated using: Lane A: 0.5 mg Hela Whole Cell Lysate. 4 uL anti-MSL2 rabbit polyclonal antibody and 15 ul of 50% Protein G agarose. Primary antibody: Anti-MSL2 rabbit polyclonal antibody, at 1:100 dilution. Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 44 kDa. Observed band size: 44 kDa.
Select
MSL2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
IP
Unconjugated, Preservative Free
100 µl/$412
MSL2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
54.2 kDa
20 µg/$150
MSL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.4 kDa
20 µg/$150
Viewing 1-25 of 29 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).