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MS4A2 / FCERI

membrane-spanning 4-domains, subfamily A, member 2

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation.

Gene Name: membrane-spanning 4-domains, subfamily A, member 2
Synonyms: MS4A2, ATOPY, FcERI, FCER1B, IGER, IgE Fc receptor subunit beta, IGHER, IGEL, APY, IgE responsiveness (atopic)
Target Sequences: NM_000139 NP_000130.1 Q01362

☰ Filters
Antibodies (12)
Proteins (4)
ELISA Kits (3)
Custom (3)
Over-Expression Lysate (2)
Primary (12)
Recombinant (2)
MS4A2 / FCERI (19)
Human (13)
Mouse (1)
Rat (1)
IHC (1)
IHC-P (1)
WB (8)
ELISA (5)
IF (1)
rabbit (11)
mouse (1)
IgG (11)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (11)
3B1 (1)
96-Well Strip Plate (3)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (4)
No (19)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
MS4A2 / FCERI Antibody - Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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MS4A2 / FCERI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
MS4A2 / FCERI Antibody - Western Blot analysis of MS4A2 expression in transfected 293T cell line by MS4A2 monoclonal antibody (M02), clone 3B1.Lane 1: MS4A2 transfected lysate(26.5 KDa).Lane 2: Non-transfected lysate.
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MS4A2 / FCERI Mouse anti-Human Monoclonal (3B1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
MS4A2 / FCERI Protein - 12.5% SDS-PAGE of human MS4A2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
52.9 kDa
10 µg/$479; 25 µg/$670
MS4A2 / FCERI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.4 kDa
100 µg/$494
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
MS4A2 / FCERI Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
MS4A2 / FCERI ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
MS4A2 / FCERI ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
MS4A2 / FCERI ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
MS4A2 / FCERI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.4 kDa
20 µg/$150
MS4A2 / FCERI Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-19 of 19 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).