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MPS1 / TTK

TTK protein kinase

MPS1 / TTK is a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Gene Name: TTK protein kinase
Family/Subfamily: Protein Kinase , TTK
Synonyms: TTK, Cancer/testis antigen 96, ESK, Esk1, MPS1, MPS1L1, Protein kinase esk, PYT, TTK protein kinase, CT96, Monopolar spindle 1-like 1
Target Sequences: NM_003318 NP_003309.2 P33981

☰ Filters
Antibodies (74)
Proteins (8)
Over-Expression Lysate (2)
Primary (74)
Recombinant (6)
MPS1 / TTK (82)
Human (58)
Mouse (25)
Rat (8)
IHC (18)
IHC-P (4)
WB (65)
ELISA (24)
Func (1)
ICC (14)
IF (3)
IP (11)
Peptide-ELISA (2)
rabbit (53)
mouse (20)
sheep (1)
Product Group
IHCPlus (1)
IgG (27)
IgG1 (15)
IgG2a (2)
IgG2a,k (1)
IgG2b (2)
monoclonal mc (20)
polyclonal pc (54)
3G7 (1)
7000 (1)
GF1 (2)
OTI13E9 (2)
OTI1D4 (2)
APC (3)
APC Conjugated (7)
Azide-free (2)
Biotin Conjugated (8)
Carrier-free (2)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (7)
Unconjugated (30)
aa527-786 (8)
aa532-786 (8)
aa570-787 (8)
aa2-32 (7)
aa6-35 (7)
aa189-464 (4)
620-700 aa (2)
C-Terminus (1)
N-Terminus (1)
aa281-481 (1)
aa642-691 (1)
aa700-750 (1)
aa800-C-term (1)
p676 (1)
No (82)
GST (1)
GST, N-terminus (1)
His-T7 (3)
Myc-DDK (Flag) (3)
Human (5)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MPS1 / TTK Antibody - Anti-MPS1 / TTK antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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MPS1 / TTK Mouse anti-Human Monoclonal (3G7) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
MPS1 / TTK Protein - Recombinant  TTK Protein Kinase By SDS-PAGE
Select
E. coli
His-T7
33.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
MPS1 / TTK Protein - Recombinant  TTK Protein Kinase By SDS-PAGE
Select
E. coli
His-T7
33.7 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
MPS1 / TTK Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using TTK (Ab-676) antibody.
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MPS1 / TTK Rabbit anti-Human Polyclonal (p676) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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MPS1 / TTK Rabbit anti-Human Polyclonal (620-700 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
MPS1 / TTK Mouse anti-Human Monoclonal (N-Terminus) Antibody
Human
Func, ICC, WB
Unconjugated
200 µg/$832
MPS1 / TTK Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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MPS1 / TTK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
MPS1 / TTK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
400 µl/$632
MPS1 / TTK Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TTK Antibody. The picture on the right is blocked with the synthesized peptide.
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MPS1 / TTK Rabbit anti-Human Polyclonal (aa642-691) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
MPS1 / TTK Rabbit anti-Human Polyclonal (620-700 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MPS1 / TTK Antibody - Western blot of MPS1 / TTK antibody.
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MPS1 / TTK Rabbit anti-Human Polyclonal (aa532-786) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
MPS1 / TTK Antibody - MPS1 Antibody in Immunofluorescence (IF)
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MPS1 / TTK Mouse anti-Human Monoclonal (7000) Antibody
Mouse, Human
ICC, IF
Unconjugated
100 µl/$518
Select
MPS1 / TTK Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
ICC, IP, WB
Unconjugated
200 µg/$832
Select
MPS1 / TTK Mouse anti-Human Monoclonal (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$1,054
Select
MPS1 / TTK Mouse anti-Human Monoclonal (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$1,054
Select
MPS1 / TTK Mouse anti-Human Monoclonal (GF1) Antibody
Human
ELISA, IF
Unconjugated
100 µl/$688
Select
MPS1 / TTK Mouse anti-Human Monoclonal (GF1) Antibody
Human
ELISA, IHC
Unconjugated
100 µl/$688
MPS1 / TTK Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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MPS1 / TTK Rabbit anti-Human Polyclonal (aa2-32) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MPS1 / TTK Antibody - 1:100 staining human skin tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MPS1 / TTK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 82 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).