Human MPO / Myeloperoxidase

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

8E6

Phycoerythrin. Also available Unconjugated or conjugated with FITC.

Chromatography

Unmodified

• Flow Cytometry
• Applications tested for the base form of this product only

Myeloperoxidase (MPO) is a glycoprotein present in the azurophil (primary) granules of myeloid cells, which appears in the myeloblast stage of myeloid cell differentiation. MPO is he most common functional protein of myeloid cells and is involved in the inflammatory response. It helps to kill microbes by breaking down peroxide in the presence of halide ions, contributing to the bactericidal function of granulocytes. The primary translation product of MPO undergoes glycosylation with production of the 89 kD heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kD MPO alpha -chain and the 14 kD MPO beta -chain. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, pH 7.2, 0.05% Sodium Azide, 1% BSA

Store at 4°C. Do not freeze. Protect from light.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P05164 NCBI: NM_000250 NP_000241.1