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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MPO / Myeloperoxidase Antibody (clone 8E6, PE) LS‑C346760
Myeloperoxidase antibody LS-C346760 is a PE-conjugated mouse monoclonal antibody to human Myeloperoxidase (MPO). Validated for Flow.
Catalog
Size
Price
LS-C346760-2
2 ml
$455
Description
Myeloperoxidase antibody LS-C346760 is a PE-conjugated mouse monoclonal antibody to human Myeloperoxidase (MPO). Validated for Flow.
Target
Human MPO / Myeloperoxidase
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [8E6]
Conjugations
Phycoerythrin. Also available Unconjugated or conjugated with FITC.
Purification
Chromatography
Modifications
Unmodified
Applications
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Usage
Myeloperoxidase (MPO) is a glycoprotein present in the azurophil (primary) granules of myeloid cells, which appears in the myeloblast stage of myeloid cell differentiation. MPO is he most common functional protein of myeloid cells and is involved in the inflammatory response. It helps to kill microbes by breaking down peroxide in the presence of halide ions, contributing to the bactericidal function of granulocytes. The primary translation product of MPO undergoes glycosylation with production of the 89 kD heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kD MPO alpha -chain and the 14 kD MPO beta -chain. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 0.05% Sodium Azide, 1% BSA
Storage
Store at 4°C. Do not freeze. Protect from light.
Restrictions
For research use only.
About MPO / Myeloperoxidase
P05164 NM_000250 NP_000241.1

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Anti-MPO / Myeloperoxidase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
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Antibody
Species: Mouse
Applications: IHC, Western blot

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Requested From: United States
Date Requested: 12/12/2018
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