Myeloperoxidase antibody LS-C346760 is a PE-conjugated mouse monoclonal antibody to human Myeloperoxidase (MPO). Validated for Flow.
Human MPO / Myeloperoxidase
(tested or 100% immunogen sequence identity)
Also available Unconjugated
or conjugated with FITC
- Flow Cytometry
- (applications tested for the base form of this product only)
Myeloperoxidase (MPO) is a glycoprotein present in the azurophil (primary) granules of myeloid cells, which appears in the myeloblast stage of myeloid cell differentiation. MPO is he most common functional protein of myeloid cells and is involved in the inflammatory response. It helps to kill microbes by breaking down peroxide in the presence of halide ions, contributing to the bactericidal function of granulocytes. The primary translation product of MPO undergoes glycosylation with production of the 89 kD heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kD MPO alpha -chain and the 14 kD MPO beta -chain. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2, 0.05% Sodium Azide, 1% BSA
Store at 4°C. Do not freeze. Protect from light.
For research use only.
About MPO / Myeloperoxidase