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MPO / Myeloperoxidase Antibody (clone 8E6, FITC) LS-C346759

Antibody

MPO / Myeloperoxidase Antibody (clone 8E6, FITC) LS-C346759

Antibody:
Mouse Monoclonal to Human MPO / Myeloperoxidase
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified
Other formats:
Price
Catalog Number
$405 
LS-C346759-2
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human MPO / Myeloperoxidase
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified
Other formats:

Specifications

Description
Myeloperoxidase antibody LS-C346759 is an FITC-conjugated mouse monoclonal antibody to human Myeloperoxidase (MPO). Validated for Flow.

Target
Human MPO / Myeloperoxidase
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
8E6
Conjugations
FITC. Also available Unconjugated or conjugated with PE.
Purification
Chromatography
Modifications
Unmodified
Applications
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Usage
Myeloperoxidase (MPO) is a glycoprotein present in the azurophil (primary) granules of myeloid cells, which appears in the myeloblast stage of myeloid cell differentiation. MPO is he most common functional protein of myeloid cells and is involved in the inflammatory response. It helps to kill microbes by breaking down peroxide in the presence of halide ions, contributing to the bactericidal function of granulocytes. The primary translation product of MPO undergoes glycosylation with production of the 89 kD heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kD MPO alpha -chain and the 14 kD MPO beta -chain. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 0.05% Sodium Azide, 1% BSA
Storage
Store at 4°C. Do not freeze. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MPO / Myeloperoxidase
P05164 NM_000250 NP_000241.1

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Requested From: United States
Date Requested: 6/27/2019
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