Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone E6-2A1] (IgG2a) to Dog IgE
Western blot, ELISA (applications tested for the base form of this product only)
Dog (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [E6-2A1]
(applications tested for the base form of this product only)
Specificity and Use
Dog IgE antibody was raised against affinity purified IgE preparation from heavily parasitized and allergic dog serum.
Recognizes canine IgE. E6-2A1 does not cross react with dog IgM, IgA, IgG1 or IgG2. Western blot analysis against affinity purified dog IgE usingdemonstrates a single major band of 62-65kD under reducing conditions.
ELISA: The antibody may be used as a capture antibody in a sandwich ELISA in combination with LS-C57551 as the detection antibody.
PBS, 0.05% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.
About Dog IgE
Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum.