MME / CD10

membrane metallo-endopeptidase

MME / CD10 is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

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Products

Antibodies (218)

Proteins (33)

ELISA Kits (17)

Type

Custom (3)

Over-Expression Lysate (14)

Primary (218)

Recombinant (19)

Sandwich (14)

Target

MME / CD10 (268)

Reactivity

Human (198)

Mouse (58)

Rat (51)

Baboon (2)

Bat (3)

Bovine (3)

Chimpanzee (3)

Cynomolgus (1)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (5)

Orangutan (3)

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Rabbit (3)

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IHC (72)

IHC-Fr (14)

IHC-P (31)

WB (139)

Flo (90)

ELISA (36)

ICC (2)

IF (12)

IP (24)

Peptide-ELISA (1)

PMA (2)

SDS-PAGE (1)

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rabbit (97)

mouse (121)

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IHCPlus (4)

PathPlus Cancer (2)

PathPlus Cancer Pathology (2)

Isotype

IgG (37)

IgG,k (1)

IgG1 (60)

IgG1,k (28)

IgG2a (3)

IgG2b (10)

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IgM (1)

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Clonality

monoclonal mc (122)

polyclonal pc (95)

recombinant monoclonal rmc (1)

Clone

113 (1)

13 (1)

2A1H5E1 (2)

3G6B11 (1)

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965CT9.1.1 (1)

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MME/1870 (2)

MME/1892 (2)

MME/1893 (2)

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OTI3D11 (2)

RXB.14 (2)

SN5c (4)

SN5c/L4-1A1 (7)

SS2/36 (1)

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UMAB236 (2)

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96-Well Microplate (4)

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Ready-to-Use (1)

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Epitope

aa411-750 (10)

aa286-428 (8)

aa32-164 (8)

aa382-538 (8)

aa455-750 (8)

aa565-750 (8)

aa506-534 (7)

aa721-747 (7)

C-Terminus (4)

aa52-750 (4)

aa492-525 (3)

aa99-132 (3)

aa272-300 (2)

aa52-246 (2)

491-540 aa, Internal (1)

CD10 (1)

Internal (1)

N-Terminus (1)

aa274-302 (1)

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Publications

No (267)

Yes (1)

Sample Type

Cell Culture Supernatants (5)

Plasma (14)

Serum (14)

Tissue Homogenates (4)

Tag

Fc (1)

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GST, N-terminus (1)

His (6)

His, N-Terminal (1)

His,N-terminus (1)

His-GST (2)

Myc-DDK (Flag) (18)

Species

Human (22)

Mouse (1)

Rat (3)

Source

293T Cells (7)

E. coli (5)

HEK 293 Cells (13)

Human (1)

Human Cells (3)

Mammalian Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (1)

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IHC-plus™ MME / CD10 Antibody (aa274-302) LS-B11799

(4.0) Rating

Antibody:

MME / CD10 Rabbit anti-Human Polyclonal (aa274-302) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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MME / CD10 Antibody (clone MEM-78, Biotin) LS-C46270

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (Biotin) (MEM-78) Antibody

Reactivity:

Human

Applications:

Flo, IP

Format:

Biotin Conjugated

Price:

0.1 mg/$337

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MME / CD10 Antibody (clone SS2/36) LS-C170888

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (SS2/36) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr

Format:

Unconjugated

Price:

0.5 ml/$328

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Human MME / CD10 (Sandwich ELISA) ELISA Kit - LS-F4981

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$798

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Rat MME / CD10 (Sandwich ELISA) ELISA Kit - LS-F8724

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$856

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MME / CD10 Antibody (clone HI10a) LS-C41007

(4.0) Rating

(1) Publication(s)

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (HI10a) Antibody

Reactivity:

Human, Monkey, Baboon

Applications:

Flo

Format:

Unconjugated

Price:

100 µg/$285

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IHC-plus™ MME / CD10 Antibody (clone EP195) LS-B12185

(4.0) Rating

Antibody:

MME / CD10 Rabbit anti-Human Monoclonal (EP195) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.05 ml/$460

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PathPlus™ MME / CD10 Antibody (clone 56C6) LS-B14553

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (56C6) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.05 ml/$460

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MME / CD10 Antibody (clone 56C6) LS-C311971

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (56C6) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$362

• Unconjugated
• Unconjugated

• Unconjugated
• Unconjugated

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MME / CD10 Antibody (aa411-750, clone UMAB235, Carrier-free) LS-C797019

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (aa411-750) (Carrier-free) (UMAB235) Antibody

Reactivity:

Human

Applications:

Flo, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

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MME / CD10 Antibody (aa52-246, clone 7D4B1) LS-C285876

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (aa52-246) (7D4B1) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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MME / CD10 Antibody LS-C12759

Antibody:

MME / CD10 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$508

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MME / CD10 Antibody (clone SN5c) LS-C43729

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (SN5c) Antibody

Reactivity:

Human

Applications:

Flo, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$385

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IHC-plus™ MME / CD10 Antibody (clone E19-P) LS-B9955

(4.0) Rating

Antibody:

MME / CD10 Rabbit anti-Human Polyclonal (E19-P) Antibody

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$460

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MME / CD10 Antibody (clone 2A1H5E1) LS-C47144

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (2A1H5E1) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

0.1 mg/$393

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MME / CD10 Antibody (clone 113, Preservative Free) LS-C818753

Antibody:

MME / CD10 Rabbit anti-Human Monoclonal (Preservative Free) (113) Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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MME / CD10 Antibody (Biotin) LS-C35423

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Biotin Conjugated

Price:

100 µg/$626

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MME / CD10 Antibody LS-C16784

Antibody:

MME / CD10 Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$826

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MME / CD10 Antibody (clone MEM-78, APC) LS-C46186

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (APC) (MEM-78) Antibody

Reactivity:

Human

Applications:

Flo, IP

Format:

APC Conjugated

Price:

100 Tests/$365

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MME / CD10 Antibody (aa411-750, clone UMAB236) LS-C797022

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (aa411-750) (UMAB236) Antibody

Reactivity:

Human

Applications:

Flo, IHC, PMA, WB

Format:

Unconjugated

Price:

100 µl/$493

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MME / CD10 Antibody (aa411-750, clone UMAB236, Carrier-free) LS-C797021

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (aa411-750) (Carrier-free) (UMAB236) Antibody

Reactivity:

Human

Applications:

Flo, IHC, PMA, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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MME / CD10 Antibody (aa272-300) LS-C164229

Antibody:

MME / CD10 Mouse anti-Human Monoclonal (aa272-300) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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MME / CD10 Antibody (C-Terminus) LS-C146479

Antibody:

MME / CD10 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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MME / CD10 Antibody (aa565-750) LS-C295562

Antibody:

MME / CD10 Rabbit anti-Human Polyclonal (aa565-750) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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PathPlus™ MME / CD10 Antibody (clone G27-P) LS-B10194

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

MME / CD10 Rabbit anti-Human Polyclonal (G27-P) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

100 µl/$460

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