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Catalog Number Size Price
LS-C388172-100 100 µg $506 
MME / CD10 Antibody - IHC-P: CD10 antibody testing of mouse kidney tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of rat spleen tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of mouse kidney tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of human B-lymphocyte cancer tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of mouse spleen tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of rat spleen tissue
MME / CD10 Antibody - Western blot testing of CD10 antibody and Lane 1: rat kidney; 2: (r) brain; 3: (r) liver; 4: human placenta; 5: (h) HeLa; 6: (h) Jurkat; 7: (h) Raji; 8: (h) 293T lysate; Routinely visualized at ~100KD
MME / CD10 Antibody - IHC-P: CD10 antibody testing of mouse kidney tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of rat spleen tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of mouse kidney tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of human B-lymphocyte cancer tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of mouse spleen tissue
MME / CD10 Antibody - IHC-P: CD10 antibody testing of rat spleen tissue
MME / CD10 Antibody - Western blot testing of CD10 antibody and Lane 1: rat kidney; 2: (r) brain; 3: (r) liver; 4: human placenta; 5: (h) HeLa; 6: (h) Jurkat; 7: (h) Raji; 8: (h) 293T lysate; Routinely visualized at ~100KD
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Polyclonal Rabbit anti‑Human MME / CD10 Antibody (aa52‑750, IHC, WB) LS‑C388172

Polyclonal Rabbit anti‑Human MME / CD10 Antibody (aa52‑750, IHC, WB) LS‑C388172

Antibody:
MME / CD10 Rabbit anti-Human Polyclonal (aa52-750) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$506
LS-C388172-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
MME / CD10 Rabbit anti-Human Polyclonal (aa52-750) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
CD10 antibody LS-C388172 is an unconjugated rabbit polyclonal antibody to CD10 (MME) (aa52-750) from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
Target
Human MME / CD10
Synonyms
MME | Atriopeptidase | CALLA | CD10 | EPN | Membrane metallo-endopeptidase | NEP | Neprilysin | Neutral endopeptidase | Neutral endopeptidase 24.11 | CD10 antigen | Enkephalinase | Neprylisin | SFE | Skin fibroblast elastase
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Human partial recombinant protein (aa52-750).
Epitope
aa52-750
Specificity
Human MME / CD10
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
CD10, also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, or common acute lymphoblastic leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimers disease. This gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, CD10 is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. CD10 has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MME / CD10
P08473 NM_000902 NP_000893.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2021