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MINK1 / MINK

misshapen-like kinase 1

Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.

Gene Name: misshapen-like kinase 1
Family/Subfamily: Protein Kinase , MSN
Synonyms: MINK1, HMINKbeta, GCK family kinase MiNK, MAP4K6, Misshapen/NIK-related kinase, MinK, Mink 1, Misshapen/NIKs-related kinase, HMINK, MEKKK 6, Mink 2, B55, ZC3, MEK kinase kinase 6, Misshapen-like kinase 1, YSK2
Target Sequences: NM_015716 NP_056531.1 Q8N4C8

☰ Filters
Antibodies (21)
Proteins (3)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (21)
Recombinant (1)
MINK1 / MINK (25)
Human (22)
Mouse (12)
Rat (6)
Bat (5)
Bovine (5)
Gibbon (3)
Hamster (1)
Horse (5)
Monkey (5)
Pig (5)
IHC (12)
IHC-P (4)
WB (13)
ELISA (9)
IF (1)
IP (3)
Peptide-ELISA (2)
rabbit (21)
Product Group
IHCPlus (2)
PathPlus Neuro (1)
IgG (14)
polyclonal pc (21)
96-Well Microplate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
C-Terminus (7)
aa755-804 (4)
Internal (3)
370-450 aa, Internal (1)
aa1-50 (1)
aa400-420 (1)
aa401-450 (1)
aa575-625 (1)
aa775-825 (1)
No (25)
Adherent Cell Cultures (1)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
MINK1 / MINK Antibody - Anti-MINK1 / MAP4K6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MINK1 / MINK Rabbit anti-Human Polyclonal (Internal) Antibody
Rat, Hamster, Pig, Horse, Bat, Mouse, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
MINK1 / MINK Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MINK1 / MINK Antibody - Anti-MINK1 / MINK antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
MINK1 / MINK Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
MINK1 / MINK Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa400-420) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MINK1 / MINK Antibody - Immunohistochemical analysis of MEKKK6 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MINK1 / MINK Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa575-625) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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MINK1 / MINK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
MINK1 / MINK Antibody - Western blot of MINK1 antibody
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MINK1 / MINK Rabbit anti-Human Polyclonal (370-450 aa, Internal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
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MINK1 / MINK Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa775-825) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
MINK1 / MINK Antibody - Western blot analysis of lysates from COLO cells, using MAP4K6 Antibody. The lane on the right is blocked with the synthesized peptide.
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa401-450) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MINK1 / MINK Antibody - MINK1 / MAP4K6 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa755-804) Antibody
Human
WB
Unconjugated
100 µl/$424
MINK1 / MINK Antibody - MINK1 / MAP4K6 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa755-804) (HRP) Antibody
Mouse, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
MINK1 / MINK Antibody - MINK1 / MAP4K6 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa755-804) (Biotin) Antibody
Mouse, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
MINK1 / MINK Antibody - MINK1 / MAP4K6 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINK1 / MINK Rabbit anti-Human Polyclonal (aa755-804) (FITC) Antibody
Mouse, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
MINK1 / MINK Protein - Purified recombinant protein MINK1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
149.6 kDa
20 µg/$1,107
MINK1 / MINK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
149.6 kDa
20 µg/$150
MINK1 / MINK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
149.6 kDa
100 µg/$494
MINK1 / MINK ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
Viewing 1-25 of 25 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).