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MICU1 / CBARA1

mitochondrial calcium uptake 1

Key regulator of mitochondrial calcium uniporter (MCU) required to increase calcium uptake by MCU when cytoplasmic calcium is high. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, respectively. MICU1 acts as a stimulator of MCU that senses calcium level via its EF-hand domains: enhances MCU opening at high Ca2+ concentration, allowing a rapid response of mitochondria to Ca2+ signals generated in the cytoplasm. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.

Gene Name: mitochondrial calcium uptake 1
Synonyms: MICU1, Ara CALC, CBARA1, CALC, EFHA3, Mitochondrial calcium uptake 1, Allergen Hom s 4, Atopy related autoantigen, Atopy-related autoantigen CALC
Target Sequences: NM_006077 NP_006068.2 Q9BPX6

☰ Filters
Antibodies (20)
Proteins (4)
Primary (20)
Recombinant (4)
MICU1 / CBARA1 (24)
Human (20)
Mouse (8)
Rat (8)
Bat (1)
Bovine (4)
Chicken (1)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Goat (4)
Guinea pig (3)
Hamster (1)
Horse (4)
Monkey (4)
Pig (4)
Rabbit (4)
Xenopus (1)
Zebrafish (1)
IHC (5)
IHC-P (4)
WB (16)
ELISA (8)
IF (1)
Peptide-ELISA (1)
rabbit (16)
mouse (3)
goat (1)
Product Group
IHCPlus (1)
IgG (12)
monoclonal mc (3)
polyclonal pc (17)
4E7 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (9)
aa52-81 (7)
aa210-259 (4)
aa113-126 (1)
No (24)
GST (2)
His, N-Terminal (1)
Myc-DDK (Flag) (1)
Human (4)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
MICU1 / CBARA1 Antibody - Anti-MICU1 / CBARA1 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MICU1 / CBARA1 Goat anti-Human Polyclonal (aa113-126) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Goat, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
MICU1 / CBARA1 Antibody - Immunohistochemical analysis of MICU1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MICU1 / CBARA1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
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MICU1 / CBARA1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MICU1 / CBARA1 Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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MICU1 / CBARA1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
MICU1 / CBARA1 Mouse anti-Human Monoclonal (4E7) Antibody
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MICU1 / CBARA1 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using MICU1 Polyclonal Antibody at dilution of 1:35(×200)
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MICU1 / CBARA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
MICU1 / CBARA1 Antibody - MICU1 / CBARA1 antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa210-259) Antibody
Human
WB
Unconjugated
100 µl/$424
MICU1 / CBARA1 Antibody - MICU1 / CBARA1 antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa210-259) (HRP) Antibody
Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
MICU1 / CBARA1 Antibody - MICU1 / CBARA1 antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa210-259) (Biotin) Antibody
Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
MICU1 / CBARA1 Antibody - MICU1 / CBARA1 antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa210-259) (FITC) Antibody
Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
MICU1 / CBARA1 Antibody - Western blot of CBAA1 Antibody in K562 cell line lysates (35 ug/lane). CBAA1 (arrow) was detected using the purified antibody.
Select
MICU1 / CBARA1 Rabbit anti-Human Polyclonal (aa52-81) Antibody
Human
WB
Unconjugated
400 µl/$393
MICU1 / CBARA1 Protein
Select
GST
36.63kDa
10 µg/$479; 25 µg/$670
MICU1 / CBARA1 Protein
Select
E. coli
His, N-Terminal
54.4 kDa
50 µg/$419
MICU1 / CBARA1 Protein - 12.5% SDS-PAGE of human CBARA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
80.8 kDa
2 µg/$439
MICU1 / CBARA1 Protein - Purified recombinant protein MICU1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
54.4 kDa
20 µg/$1,107
Viewing 1-24 of 24 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).