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Catalog Number Size Price
LS-C744229-1 1 ml $554 
Antibody

Monoclonal Mouse Melanoma Antigen NKI/C3 Antibody (clone NKI/C3, IHC) LS‑C744229

Monoclonal Mouse Melanoma Antigen NKI/C3 Antibody (clone NKI/C3, IHC) LS‑C744229

Antibody:
Melanoma Antigen NKI/C3 Mouse Monoclonal (NKI/C3) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$554
LS-C744229-1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Melanoma Antigen NKI/C3 Mouse Monoclonal (NKI/C3) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
C3 antibody LS-C744229 is an unconjugated mouse monoclonal antibody to human C3 (Melanoma Antigen NKI). Validated for IHC.
Target
Melanoma Antigen NKI/C3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
NKI/C3
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Protein extract of human melanoma cell line
Applications
  • IHC - Paraffin (1:10 - 1:20)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
No pre-treatment with proteases necessary, improved staining may be achieved with antigen retrieval The antibody NKI-C3 binds to a melanoma-associated antigen, which is mainly expressed in the cytoplasm of melanoma cells and naevus cellnaevi. The antibody doesn't react with normal melanocytes or other normal cells with the exception of mast cells, histiocytes, salivary gland, bronchial, pancreatic and prostate epithelia. To avoid True positive results in diagnosis the antibody should only be used in combination with non cross-reacting melanoma markers (e.g. HMB45 Art. No. ME100 and ME500). Melanocytes are pigmented Melanin containing cells, which are mainly located in the epidermis, protecting tissues from irradiation by sun beams (UVB). In melanoic tumours characteristic proteins are over-expressed, which in part are defined by specific antibodies. NKI/C3 in Western Blot stains diffuse protein bands in a range of 25 to 100 kDa from cytoplasm of melanoma cells 25-100 kDa peptide band in immuno blot of human melanoma.
Presentation
PBS, pH 7.3, 0.09% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/24/2022