MECP2 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa465-478 of mouse MeCP2 (C-PRPNREEPVDSRTP) with an N-terminal cysteine added for conjugation purposes.
Recognizes MeCP2, Mr 75kD. A protein at ~75kD was also observed in HeLa nuclear extract. This protein was competed by pre-incubation of the antibody with the immunogenic peptide, suggesting that some HeLa strains contain MeCP2 or a related protein, contrary to a previous report. Species cross-reactivity: Mouse and rat. Predicted to cross-react with human based on the conservation of the immunogenic sequence.
PBS, pH 7.2, No preservatives added
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