MCM6

minichromosome maintenance complex component 6

MCM6 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.

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Products

Antibodies (35)

Proteins (5)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (35)

Recombinant (3)

Sandwich (1)

Target

MCM6 (41)

Reactivity

Human (36)

Mouse (14)

Rat (10)

Bovine (9)

Chimpanzee (6)

Dog (9)

Gibbon (6)

Guinea pig (9)

Horse (9)

Monkey (1)

Pig (3)

Rabbit (9)

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Application

IHC (29)

IHC-Fr (1)

IHC-P (13)

WB (32)

ELISA (13)

ICC (1)

IF (2)

IP (1)

Peptide-ELISA (1)

Host

rabbit (32)

mouse (1)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (28)

Clonality

polyclonal pc (35)

Format

96-Well Strip Plate (1)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (21)

Epitope

C-Terminus (8)

aa80-109 (7)

Internal (4)

aa775-C-term (4)

aa562-821 (2)

331-380 aa, Internal (1)

aa589-605 (1)

Publications

No (41)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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MCM6 Antibody (aa589-605) LS-C312918

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa589-605) Antibody

Reactivity:

Human, Monkey

Applications:

ICC, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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MCM6 Antibody (aa562-821) LS-C377439

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa562-821) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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MCM6 Antibody (C-Terminus) LS-B6803

Antibody:

MCM6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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MCM6 Antibody (C-Terminus, HRP) LS-C434553

Antibody:

MCM6 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Bovine, Horse, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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MCM6 Antibody (C-Terminus, Biotin) LS-C434551

Antibody:

MCM6 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Bovine, Horse, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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MCM6 Antibody (C-Terminus, FITC) LS-C434552

Antibody:

MCM6 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Bovine, Horse, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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MCM6 Antibody LS-C331789

Antibody:

MCM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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MCM6 Antibody LS-C666682

Antibody:

MCM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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MCM6 Antibody LS-C308922

Antibody:

MCM6 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$705

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MCM6 Antibody LS-C400876

Antibody:

MCM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MCM6 Antibody LS-C404130

Antibody:

MCM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MCM6 Antibody (aa562-821) LS-C377440

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa562-821) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

MCM6 Antibody (aa80-109) LS-C322914

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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MCM6 Antibody (aa80-109, Biotin) LS-C226873

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MCM6 Antibody (aa80-109, FITC) LS-C226874

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MCM6 Antibody (aa80-109, APC) LS-C226872

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MCM6 Antibody (aa80-109, Azide-free, HRP) LS-C226876

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MCM6 Antibody (aa80-109, PE) LS-C226878

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

MCM6 Antibody (C-Terminus) LS-C31430

Antibody:

MCM6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

Select

MCM6 Antibody (C-Terminus, FITC) LS-C434555

Antibody:

MCM6 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Bovine, Horse, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• FITC

• Unconjugated
• FITC

Select

MCM6 Antibody (aa80-109) LS-C164096

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa80-109) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MCM6 Antibody (aa775-C-term) LS-C287057

Antibody:

MCM6 Goat anti-Human Polyclonal (aa775-C-term) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

MCM6 Antibody LS-C806289

Antibody:

MCM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MCM6 Antibody LS-C192830

Antibody:

MCM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

MCM6 Antibody (aa775-C-term) LS-C287114

Antibody:

MCM6 Rabbit anti-Human Polyclonal (aa775-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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