MCM4

minichromosome maintenance complex component 4

MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.

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Products

Antibodies (60)

Proteins (8)

ELISA Kits (1)

Type

Cell-Based (1)

Over-Expression Lysate (4)

Primary (60)

Recombinant (4)

Target

MCM4 (69)

Reactivity

Human (60)

Mouse (32)

Rat (15)

Bat (9)

Bovine (12)

Chimpanzee (9)

Dog (9)

Gibbon (12)

Guinea pig (6)

Hamster (9)

Horse (6)

Monkey (10)

Pig (9)

Rabbit (9)

Xenopus (6)

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Application

IHC (24)

IHC-P (6)

WB (49)

ELISA (19)

IF (2)

Peptide-ELISA (2)

Host

rabbit (51)

mouse (7)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (44)

IgG2a,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (54)

Format

96-Well Microplate (1)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (8)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (3)

Unconjugated (30)

Epitope

aa637-665 (7)

C-Terminus (4)

aa411-460 (4)

aa80-129 (4)

aa97-146 (4)

pSer54 (4)

30-110 aa (2)

aa325-375 (2)

aa750-800 (2)

N-Terminus (1)

Pro50 (1)

aa20-69 (1)

aa267-366 (1)

p54 (1)

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Publications

No (69)

Sample Type

Adherent Cell Cultures (1)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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MCM4 Antibody (N-Terminus) LS-C352496

Antibody:

MCM4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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MCM4 Antibody (30-110 aa) LS-C380950

Antibody:

MCM4 Rabbit anti-Human Polyclonal (30-110 aa) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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MCM4 Antibody LS-C670066

Antibody:

MCM4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MCM4 Antibody LS-C308919

Antibody:

MCM4 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$705

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Mouse/Human MCM4 (Cell-Based ELISA) ELISA Kit - LS-F2134

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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MCM4 Antibody LS-C405717

Antibody:

MCM4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MCM4 Antibody LS-C332328

Antibody:

MCM4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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IHC-plus™ MCM4 Antibody (aa325-375) LS-B17037

(4.0) Rating

Antibody:

MCM4 Goat anti-Human Polyclonal (aa325-375) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µl/$460

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MCM4 Antibody (aa325-375) LS-C287055

Antibody:

MCM4 Goat anti-Human Polyclonal (aa325-375) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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MCM4 Antibody LS-C751925

Antibody:

MCM4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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MCM4 Antibody (30-110 aa) LS-C384460

Antibody:

MCM4 Rabbit anti-Human Polyclonal (30-110 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MCM4 Antibody (aa637-665) LS-C322913

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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MCM4 Antibody (aa637-665, Biotin) LS-C226867

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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MCM4 Antibody (aa637-665, FITC) LS-C226868

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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MCM4 Antibody (aa637-665, PE) LS-C226870

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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MCM4 Antibody (aa637-665, APC) LS-C226866

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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MCM4 Antibody (aa637-665, Azide-free, HRP) LS-C226869

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

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MCM4 Antibody (p54) LS-C822310

Antibody:

MCM4 Rabbit anti-Human Polyclonal (p54) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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MCM4 Antibody (aa20-69) LS-C117882

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa20-69) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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MCM4 Antibody (Pro50) LS-C177430

Antibody:

MCM4 Rabbit anti-Human Polyclonal (Pro50) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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MCM4 Antibody (aa637-665) LS-C164093

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa637-665) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MCM4 Antibody LS-C341244

Antibody:

MCM4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

MCM4 Antibody (phospho-Ser54) LS-C313609

Antibody:

MCM4 Rabbit anti-Human Polyclonal (pSer54) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$328; 100 µl/$419

Select

MCM4 Antibody LS-C768090

Antibody:

MCM4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

MCM4 Antibody (aa750-800) LS-C287113

Antibody:

MCM4 Rabbit anti-Human Polyclonal (aa750-800) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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