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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2231-50 | 50 µg (1 mg/ml) | $535 |
IHC‑plus™ Monoclonal Mouse anti‑Human MBP / Myelin Basic Protein Antibody (aa130‑136, IHC, WB) LS‑B2231
IHC‑plus™ Monoclonal Mouse anti‑Human MBP / Myelin Basic Protein Antibody (aa130‑136, IHC, WB) LS‑B2231
Note: This antibody replaces LS-C25696
Antibody:
MBP / Myelin Basic Protein Mouse anti-Human Monoclonal (aa130-136) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, ELISA
Reactivity:
Human, Mouse, Rat, Goat, Rabbit, Sheep, Primate
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
MBP / Myelin Basic Protein Mouse anti-Human Monoclonal (aa130-136) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, ELISA
Reactivity:
Human, Mouse, Rat, Goat, Rabbit, Sheep, Primate
Format:
Unconjugated, Unmodified
Specifications
Description
Myelin Basic Protein antibody LS-B2231 is an unconjugated mouse monoclonal antibody to Myelin Basic Protein (MBP) (aa130-136) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human MBP / Myelin Basic Protein
Synonyms
MBP | Myelin A1 protein | Myelin basic protein
Host
Mouse
Reactivity
Human, Mouse, Rat, Goat, Rabbit, Sheep, Primate
(tested or 100% immunogen sequence identity)
Clonality
IgG2b
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Purified human myelin basic protein.
Epitope
aa130-136
Specificity
Recognizes residues 130-136 in human myelin basic protein (21.5kD and 18.5kD molecular forms).
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- IHC - Frozen
- Western blot (1 - 2 µg/ml)
- ELISA (10 - 20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2231 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2231 was determined to be 5 ug/ml.
Presentation
PBS, pH 7.4, no preservatives.
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MBP / Myelin Basic Protein
Validation
Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ MBP / Myelin Basic Protein Antibody (aa130-136) for IHC, WB/Western, ELISA LS-B2231 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Cranial nerve involvement in patients with MOG antibody-associated disease. Cobo-Calvo A, Ayrignac X, Kerschen P, Horellou P, Cotton F, Labauge P, Vukusic S, Deiva K, Serguera C, Marignier R. Neurology(R) neuroimmunology & neuroinflammation. 2019 February;6:e543.
Wharton's Jelly Mesenchymal Stem Cells Protect the Immature Brain in Rats and Modulate Cell Fate. Martin Mueller , Byron Oppliger , Marianne Joerger-Messerli , Ursula Reinhart , Eytan Barnea, Michael Paidas, Boris W Kramer , Daniel V Surbek , Andreina Schoeberlein. The Breast : official journal of the European Society of Mastology. 2017 Feb;26:239-248.
Immunoreactivity of myelin-associated oligodendrocytic basic protein in Lewy bodies. Tomoya Kon, Kunikazu Tanji, Fumiaki Mori, Akari Kimura, Akiyoshi Kakita, Koichi Wakabayashi. Neuropathology : official journal of the Japanese Society of Neuropathology. 2019 August;39:279-285.
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Featured Products
Species:
Rat
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Bovine, Human, Mouse, Rat, Guinea pig, Pig, Rabbit, Sheep, Chicken, Mammal
Applications:
IHC, IHC - Paraffin, Western blot, ELISA, Radioimmunoassay
Species:
Human, Rat
Applications:
Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Reactivity:
Rat
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
