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MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
| Gene Name: | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| Synonyms: | MAFB, KRML, Maf-B, MCTO, Transcription factor MafB |
| Target Sequences: | NM_005461 NP_005452.2 Q9Y5Q3 |
Publications (1)
1
Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development. Hochane M, van den Berg PR, Fan X, Bérenger-Currias N, Adegeest E, Bialecka M, Nieveen M, Menschaart M, Chuva de Sousa Lopes SM, Semrau S. PLoS biology. 2019 February;17:e3000152. [Full Text Article]
[PubMed:30789893]
[PMC:PMC6400406]
Related Antibodies: LS-C336952.
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MAFB Mouse anti-Human Monoclonal (OTI2A6) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
MAFB Mouse anti-Human Monoclonal (aa32-320) (Carrier-free) (OTI2A6) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
MAFB Mouse anti-Human Monoclonal (aa32-320) (OTI1E9) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
MAFB Mouse anti-Human Monoclonal (aa32-320) (Carrier-free) (OTI1E9) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
MAFB Rabbit anti-Human Polyclonal (aa41-90) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
MAFB Rabbit anti-Human Polyclonal (aa273-323) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MAFB Rabbit anti-Human Polyclonal (aa251-300) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MAFB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MAFB Mouse anti-Human Monoclonal (OTI1F1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
MAFB Mouse anti-Human Monoclonal (aa32-320) (Carrier-free) (OTI1F1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
MAFB Rabbit Recombinant Monoclonal Antibody
ICC, IHC, IP, WB
Unconjugated
10 µl/$299; 100 µl/$548
MAFB Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
MAFB Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
MAFB Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
MAFB Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
MAFB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MAFB Mouse anti-Human Monoclonal (OTI3F6) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
MAFB Mouse anti-Human Monoclonal (aa32-320) (Carrier-free) (OTI3F6) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
MAFB Rabbit anti-Human Polyclonal (aa266-292) Antibody
Human
Flo, WB
Unconjugated
200 µl/$734
MAFB Rabbit anti-Human Polyclonal (aa266-292) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
MAFB Rabbit anti-Human Polyclonal (aa266-292) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
MAFB Rabbit anti-Human Polyclonal (aa266-292) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
MAFB Rabbit anti-Human Polyclonal (aa266-292) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
MAFB Rabbit anti-Human Polyclonal (aa266-292) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
MAFB Rabbit anti-Human Polyclonal (aa266-292) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
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