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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C391457-100 100 µg (1 mg/ml) $465 
Macrophage + Histiocytoma Marker Antibody - Formalin-fixed, paraffin-embedded human Histiocytoma stained with Macrophage antibody (D11).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Macrophage + Histiocytoma Marker Antibody - Formalin-fixed, paraffin-embedded human Histiocytoma stained with Macrophage antibody (D11).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Macrophage + Histiocytoma Marker Antibody - Formalin-fixed, paraffin-embedded human Histiocytoma stained with Macrophage antibody (D11).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Macrophage + Histiocytoma Marker Antibody - Formalin-fixed, paraffin-embedded human Histiocytoma stained with Macrophage antibody (D11).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Macrophage + Histiocytoma Marker Antibody (clone D11, Azide‑free) LS‑C391457

Macrophage + Histiocytoma Marker Antibody (clone D11, Azide‑free) LS‑C391457

Antibody:
Mouse Monoclonal to Human Macrophage + Histiocytoma Marker
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free
Other formats:
Price
Catalog Number
$465 
LS-C391457-100
100 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human Macrophage + Histiocytoma Marker
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free
Other formats:

Specifications

Description
Macrophage + Histiocytoma Marker antibody LS-C391457 is an unconjugated mouse monoclonal antibody to human Macrophage + Histiocytoma Marker. Validated for IHC.
Target
Human Macrophage + Histiocytoma Marker
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat, Pig
Clonality
IgG1,k Monoclonal
Clone
D11
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free. Also available Unmodified or Ready-to-Use.
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Membrane preparation from human hepatocytes.
Specificity
Human Macrophage + Histiocytoma Marker
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this mAb and a standard CD68 mAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This mAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This mAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages. Optimal dilution of the Macrophage / Histiocytoma Marker antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Presentation
Sterile Solution PBS
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Requested From: United States
Date Requested: 10/16/2019