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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LTK Antibody (aa800‑864) IHC‑plus™ LS‑B2050 Best Seller
Note: This antibody replaces LS-C736
LTK antibody LS-B2050 is an unconjugated rabbit polyclonal antibody to human LTK. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2050-50
50 µg (0.5 mg/ml)
Unavailable

Popular LTK Products

Antibody
Species: Human
Applications: Western blot, ELISA
Anti-LTK antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11348 dilution 1:50.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human, Mouse
Applications: IHC, Immunofluorescence, Western blot, ELISA
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

LTK antibody LS-B2050 is an unconjugated rabbit polyclonal antibody to human LTK. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About LTK
Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. P29376 NM_002344 NP_002335.2

LTK Antibody, Leukocyte tyrosine kinase Antibody, Protein tyrosine kinase 1 Antibody, TYK1 Antibody


Specifications

Target
Human LTK
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot (0.5 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
LTK antibody was raised against synthetic peptide from human LTK.
Epitope
aa800-864
Specificity
The amino acid sequence used as immunogen has 100% identity in human isoforms 1 and 2, and 81% homologous in mouse isoforms A, B, C, and D, and rat. LTK is an 864 amino acid protein with an approximate molecular weight of 94 kD.
Usage
Immunohistochemistry: LS-B2050 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2050 was determined to be 10 ug/ml.
Presentation
PBS, 0.2% gelatin, 0.05% sodium azide.
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Immunohistochemistry

Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.
Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.

Western blot

Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.
Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.

Immunohistochemistry

Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.
Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.

Western blot

Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.
Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.

Immunohistochemistry

Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.
Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.

Western blot

Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.
Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.

Immunohistochemistry

Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.
Anti-LTK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2050 concentration 10 ug/ml.

Western blot

Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.
Western blot of LTK in human K562 cell lysate using antibody at 1 ug/ml.

Requested From: 
Date Requested: 7/18/2018

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