LRP2 / Megalin

low density lipoprotein receptor-related protein 2

LRP2 / Megalin, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).

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Products

Antibodies (33)

ELISA Kits (8)

Proteins (2)

Type

Primary (33)

Recombinant (2)

Sandwich (8)

Target

LRP2 / Megalin (43)

Reactivity

Human (35)

Mouse (7)

Rat (8)

Application

IHC (13)

IHC-P (9)

WB (14)

ELISA (12)

Peptide-ELISA (1)

Host

rabbit (33)

Product Group

IHCPlus (2)

PathPlus Cancer (1)

Isotype

IgG (20)

Clonality

polyclonal pc (33)

Format

96-Well Microplate (1)

96-Well Strip Plate (7)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Preservative Free (2)

Unconjugated (15)

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Epitope

C-Terminus (8)

aa4035-4184 (8)

N-Terminus (1)

Publications

No (43)

Sample Type

Cell Culture Supernatants (2)

Plasma (8)

Serum (8)

Tissue Homogenates (5)

Tag

6His, N-terminus (2)

Species

Human (2)

Source

E. coli (1)

Yeast (1)

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IHC-plus™ LRP2 / Megalin Antibody LS-B15411

(4.0) Rating

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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LRP2 / Megalin Antibody (C-Terminus) LS-C145128

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$468

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LRP2 / Megalin Antibody (N-Terminus) LS-C47074

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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Mouse LRP2 / Megalin (Sandwich ELISA) ELISA Kit - LS-F13513

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Rat LRP2 / Megalin (Sandwich ELISA) ELISA Kit - LS-F13514

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Human LRP2 / Megalin (Sandwich ELISA) ELISA Kit - LS-F11978

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human LRP2 / Megalin Protein (Recombinant 6His, N-terminus) (aa1186-1389) - LS-G23013

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

24.2 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human LRP2 / Megalin (Sandwich ELISA) ELISA Kit - LS-F6367

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$834

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LRP2 / Megalin Antibody (aa4035-4184) LS-B15008

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Rat LRP2 / Megalin (Sandwich ELISA) ELISA Kit - LS-F33155

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Human LRP2 / Megalin Protein (Recombinant 6His, N-terminus) (aa4035-4184) - LS-G25215

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

21.1 kDa

Price:

10 µg/$252; 50 µg/$315; 100 µg/$417; 200 µg/$522; 1 mg/$1,404; 500 µg/$1,034; 5 mg/$2,303; 2 mg/$1,565

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LRP2 / Megalin Antibody LS-C804391

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PathPlus™ LRP2 / Megalin Antibody LS-B16777

Cancer

(5.0) Rating

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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LRP2 / Megalin Antibody LS-C402355

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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LRP2 / Megalin Antibody (aa4035-4184, HRP) LS-C712241

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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Human LRP2 / Megalin (Sandwich ELISA) ELISA Kit - LS-F33154

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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LRP2 / Megalin Antibody LS-C670613

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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LRP2 / Megalin Antibody LS-C751619

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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LRP2 / Megalin Antibody LS-C670615

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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LRP2 / Megalin Antibody (C-Terminus) LS-C330507

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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LRP2 / Megalin Antibody (C-Terminus, Biotin) LS-C278936

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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LRP2 / Megalin Antibody (C-Terminus, FITC) LS-C278937

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

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LRP2 / Megalin Antibody (C-Terminus, PE) LS-C278939

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

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LRP2 / Megalin Antibody (C-Terminus, APC) LS-C278935

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

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LRP2 / Megalin Antibody (C-Terminus, Azide-free, HRP) LS-C278938

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

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