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LPAR1 / LPA1 / EDG2
lysophosphatidic acid receptor 1
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene
| Gene Name: | lysophosphatidic acid receptor 1 |
| Family/Subfamily: | GPCR , Lysophospholipid/Lysosphingolipid |
| Synonyms: | LPAR1, EDG-2, EDG2, Gpcr26, Rec.1.3, Vzg-1, Ventricular zone gene 1, LPA receptor 1, LPA-1, LPA1, Mrec1.3, VZG1 |
| Target Sequences: | NM_001401 NP_001392.2 Q92633 |
Publications (3)
1
Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA). Park EY, Kazlauskas A. Bioscience reports. 2012 32:393-400. (WB; Rat)
[PubMed:22639801]
[PMC:PMC3392100]
2
Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascade. Miyabe Y, Miyabe C, Iwai Y, Yokoyama W, Sekine C, Sugimoto K, Harigai M, Miyasaka M, Miyasaka N, Nanki T. Arthritis research & therapy. 2014 16:461. (WB; Human)
[Full Text Article]
[PubMed:25273676]
[PMC:PMC4203966]
Related Antibodies: LS-C173399.
3
Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors in adenomyosis. Yang B, Wang L, Wan X, Li Y, Yu X, Qin Y, Luo Y, Wang F, Huang O. BMC women's health. 2017 November;17:118. (Human)
[Full Text Article]
[PubMed:29178922]
[PMC:PMC5702234]
Related Antibodies: LS-B1498.
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LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa342-359) Antibody
Xenopus, Chicken, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Mouse, Dog, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
1 Each/$485
Neuroscience
Fast Shipping
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Xenopus, Chicken, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
LPAR1 / LPA1 / EDG2 Mouse anti-Human Monoclonal (OTI1G6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$450
LPAR1 / LPA1 / EDG2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa5-54) Antibody
Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Sheep, Bovine, Rat, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa21-50) Antibody
Human
WB
Unconjugated
400 µl/$393
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa342-359) Antibody
Human
WB
Unconjugated
100 µl/$289
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$386
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (Trp45) Antibody
Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
LPAR1 / LPA1 / EDG2 Mouse anti-Human Monoclonal (2E2) Antibody
Human
ELISA
Unconjugated
100 µg/$423
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (20-100 aa, N-terminal) Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Sandwich
96-Well Strip Plate
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa21-50) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa21-50) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal (aa21-50) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
LPAR1 / LPA1 / EDG2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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