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LHCGR / LHR / LH Receptor
luteinizing hormone/choriogonadotropin receptor
LHCGR is a Glycoprotein Hormone Receptor for both luteinizing hormone and choriogonadotropin. It is expressed in the reproductive organs of both males and females. In males, the luteinizing hormone/choriogonadotropin receptor is involved in the development and function of Leydig cells. Mutations in this gonadotropin receptor can result in disorders of male secondary sexual character development, such as familial male precocious puperty and male pseudohermaphroditism, or lead to adenomas of the testis. In females, inactivating mutations of LHCGR cause hypergonadotrophic hypogonadism with primary amenorrhea or oligomenorrhea, cystic ovaries, and infertility. LHCGR has many alternatively spliced isoforms that affect where this gene is expressed.
| Gene Name: | luteinizing hormone/choriogonadotropin receptor |
| Family/Subfamily: | GPCR , Glycoprotein hormone |
| Synonyms: | LHCGR, HCG receptor, HHG, LCGR, LH/CGR, LHR, LH receptor, LHRHR, Lutropin receptor, LGR2, LH/CG-R, LSH-R, ULG5, Luteinizing hormone receptor |
| Target Sequences: | NM_000233 NP_000224.2 P22888 |
Publications (6)
1
Effect of stallion age on the expression of LH and FSH receptors and aromatase P450 in equine male reproductive tissues. Herrera-Luna CV, Scarlet D, Walter I, Aurich C. Reproduction, fertility, and development. 2016 28:2016-2026. (WB, IHC-P; Human)
[Full Text Article]
[PubMed:26143654]
Related Antibodies: LS-C312710.
2
Immunohistochemistry in Investigative and Toxicologic Pathology. Kyathanahalli S Janardhan, Heather Jensen, Natasha P Clayton, Ronald A Herbert. Toxicologic pathology. 2018 July;46:488-510. [Full Text Article]
[PubMed:29966501]
[PMC:PMC6033701]
Related Antibodies: LS-C312710.
3
Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype. Janelle Cheung, Noor A Lokman, Riya D Abraham, Anne M Macpherson, Eunice Lee, Frank Grutzner, Nicolae Ghinea, Martin K Oehler , Carmela Ricciardelli. International journal of molecular sciences. 2020 Dec;22:71. [Full Text Article]
[PubMed:33374698]
[PMC:PMC7793521]
Related Antibodies: LS-C334599.
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LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa127-143) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa622-699) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (590-670 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa27-363) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa27-363) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa27-363) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa27-363) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (8G9A2) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$372
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa27-362) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Mammalian Cells
6His, N-terminus
100 µg/$1,116; 20 µg/$461; 1 mg/$3,921
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (LHCGR/1416) Antibody
Human
Flo, IF, WB
Unconjugated
20 µg/$371; 100 µg/$574
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (Azide-free, BSA-free) (LHCGR/1416) Antibody
Human
Flo, IF, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (LHCGR/1415) Antibody
Human
Flo, IF, WB
Unconjugated
20 µg/$371; 100 µg/$574
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (Azide-free, BSA-free) (LHCGR/1415) Antibody
Human
Flo, IF, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (LHCGR/1417) Antibody
Human
Flo, IF, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
LHCGR / LHR / LH Receptor Mouse anti-Human Monoclonal (Azide-free, BSA-free) (LHCGR/1417) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
LHCGR / LHR / LH Receptor Rabbit anti-Human Polyclonal (aa621-670) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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