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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LGMN / Legumain Antibody (aa18‑435, Biotin) LS‑C687238
Legumain antibody LS-C687238 is a biotin-conjugated rabbit polyclonal antibody to mouse Legumain (LGMN). Validated for IHC and WB.
Catalog
Size
Price
LS-C687238-20
20 µl
Unavailable
LS-C687238-100
100 µl
Unavailable
LS-C687238-200
200 µl
Unavailable
LS-C687238-1
1 ml
Unavailable
LS-C687238-10
10 ml
Unavailable

Popular LGMN / Legumain Products

LGMN / Legumain antibody Western Blot of Fetal Brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Sheep
Applications: Western blot
Anti-LGMN / Legumain antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Mouse
Applications: ICC, Western blot
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Legumain antibody LS-C687238 is a biotin-conjugated rabbit polyclonal antibody to mouse Legumain (LGMN). Validated for IHC and WB.
About LGMN / Legumain
LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. Q99538 NM_005606 NP_005597.3

LGMN Antibody, AEP Antibody, LGMN1 Antibody, Protease, cysteine 1 Antibody, Asparaginyl endopeptidase Antibody, Cysteine protease 1 Antibody, Legumain Antibody, PRSC1 Antibody


Specifications

Target
Mouse LGMN / Legumain
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • IHC
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
LGMN / Legumain antibody was raised against recombinant LGMN (Val18-Tyr435)
Epitope
aa18-435
Specificity
The antibody is a rabbit polyclonal antibody raised against LGMN. It has been selected for its ability to recognize LGMN in immunohistochemical staining and western blotting.
Presentation
PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Requested From: 
Date Requested: 7/20/2018

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