LGMN / Legumain

legumain

LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.

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Products

Antibodies (55)

Proteins (19)

ELISA Kits (12)

Type

Custom (4)

Over-Expression Lysate (4)

Primary (55)

Recombinant (15)

Sandwich (8)

Target

LGMN / Legumain (86)

Reactivity

Human (50)

Mouse (27)

Rat (16)

Bovine (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Monkey (6)

Orangutan (6)

Pig (1)

Rabbit (3)

Sheep (3)

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Application

IHC (7)

IHC-P (7)

WB (43)

ELISA (16)

IF (1)

IP (2)

Host

rabbit (48)

mouse (7)

Product Group

IHCPlus (3)

Isotype

IgG (20)

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (49)

Clone

M1 (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (10)

APC (2)

APC Conjugated (5)

Azide-free (1)

Biotin Conjugated (8)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (5)

Unconjugated (17)

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Epitope

aa18-433 (8)

aa18-435 (8)

aa83-112 (7)

aa181-230 (4)

aa214-263 (4)

aa1-434 (1)

Publications

No (86)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Citrate Plasma (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (8)

Serum (9)

Tissue Homogenates (4)

Tag

10His, N-terminus + Myc, C-terminus (2)

6His, C-terminus (4)

6His, N-terminus (5)

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Crab-eating macaque (2)

Human (9)

Mouse (6)

Source

293T Cells (2)

Baculovirus (1)

E. coli (5)

HEK 293 Cells (3)

Human Cells (3)

Mammalian Cells (2)

Wheat Germ Extract (1)

Yeast (2)

Purification

Purified (10)

Low Endotoxin Level

Low endotoxin level (5)

Select

LGMN / Legumain Antibody (aa214-263) LS-C152206

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa214-263) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IHC-plus™ LGMN / Legumain Antibody LS-B15611

(4.0) Rating

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F11947

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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IHC-plus™ LGMN / Legumain Antibody (aa83-112) LS-B9325

(4.0) Rating

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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LGMN / Legumain Antibody (aa18-435) LS-C372983

Antibody:

LGMN / Legumain Rabbit anti-Mouse Polyclonal (aa18-435) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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LGMN / Legumain Antibody LS-C488085

Antibody:

LGMN / Legumain Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$412

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IHC-plus™ LGMN / Legumain Antibody (aa83-112) LS-B15725

(4.0) Rating

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$485

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LGMN / Legumain Antibody (aa83-112, Biotin) LS-C261861

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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LGMN / Legumain Antibody (aa83-112, FITC) LS-C261862

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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LGMN / Legumain Antibody (aa83-112, APC) LS-C261860

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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LGMN / Legumain Antibody (aa83-112, PE) LS-C261865

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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LGMN / Legumain Antibody (aa83-112, Azide-free, HRP) LS-C261863

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa83-112) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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Mouse LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F16407

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human LGMN / Legumain Protein (Recombinant 6His, N-terminus) (aa18-433) - LS-G24951

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

51.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse LGMN / Legumain (Sandwich ELISA) ELISA Kit - LS-F8653

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

Select

LGMN / Legumain Antibody LS-C670576

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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LGMN / Legumain Antibody LS-C309174

Antibody:

LGMN / Legumain Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

LGMN / Legumain Antibody LS-C780747

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

LGMN / Legumain Antibody LS-C832846

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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LGMN / Legumain Antibody LS-C310868

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

Select

LGMN / Legumain Antibody LS-C488084

Antibody:

LGMN / Legumain Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

LGMN / Legumain Antibody (aa1-434, clone M1) LS-C309173

Antibody:

LGMN / Legumain Mouse anti-Human Monoclonal (aa1-434) (M1) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$705

Select

LGMN / Legumain Antibody (aa18-433) LS-C372984

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal (aa18-433) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

LGMN / Legumain Antibody LS-C488083

Antibody:

LGMN / Legumain Rabbit anti-Pig Polyclonal Antibody

Reactivity:

Pig

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

LGMN / Legumain Antibody LS-C310871

Antibody:

LGMN / Legumain Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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