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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LGMN / Legumain Antibody (aa18‑433, APC) LS‑C717890
Legumain antibody LS-C717890 is an APC-conjugated rabbit polyclonal antibody to Legumain (LGMN) from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C717890-20
20 µl
$225
LS-C717890-100
100 µl
$305
LS-C717890-200
200 µl
$375
LS-C717890-1
1 ml
$785
LS-C717890-10
10 ml
$3,105

Popular LGMN / Legumain Products

LGMN / Legumain antibody Western Blot of Fetal Brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Sheep
Applications: Western blot
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-LGMN / Legumain antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Mouse
Applications: ICC, Western blot
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Legumain antibody LS-C717890 is an APC-conjugated rabbit polyclonal antibody to Legumain (LGMN) from human, mouse and rat. Validated for IHC and WB.
About LGMN / Legumain
LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. Q99538 NM_005606 NP_005597.3

LGMN Antibody, AEP Antibody, LGMN1 Antibody, Protease, cysteine 1 Antibody, Asparaginyl endopeptidase Antibody, Cysteine protease 1 Antibody, Legumain Antibody, PRSC1 Antibody


Specifications

Target
Human LGMN / Legumain
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Allophycocyanin. Also available Unconjugated or conjugated with Biotin, FITC, Biotin, FITC, Cy3, HRP, PE, APC, Cy7.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
LGMN / Legumain antibody was raised against recombinant LGMN (Val18-Tyr433)
Epitope
aa18-433
Specificity
The antibody is a rabbit polyclonal antibody raised against LGMN. It has been selected for its ability to recognize LGMN in immunohistochemical staining and western blotting.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.

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Images

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Western blot

Western blot of LGMN / Legumain antibody.
Western blot of LGMN / Legumain antibody.

Requested From: United States
Date Requested: 9/25/2018

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