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Catalog Number Size Price
LS-C391433-100 100 µg (1 mg/ml) $550 
Lewis A Blood Group Antigen Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with Blood Group Lewis a antibody (SPM279).  This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti‑Human Lewis A Blood Group Antigen Antibody (clone SPM279, Azide‑free,BSA‑free, IHC) LS‑C391433

Monoclonal Mouse anti‑Human Lewis A Blood Group Antigen Antibody (clone SPM279, Azide‑free,BSA‑free, IHC) LS‑C391433

Antibody:
Lewis A Blood Group Antigen Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM279) Antibody
Application:
IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Price
Catalog Number
$550
LS-C391433-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
Lewis A Blood Group Antigen Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM279) Antibody
Application:
IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Azide-free, BSA-free
Other formats:

Specifications

Description
Lewis A Blood Group Antigen antibody LS-C391433 is an unconjugated mouse monoclonal antibody to Lewis A Blood Group Antigen from human. It is reactive with human and mouse. Validated for IHC.
Target
Human Lewis A Blood Group Antigen
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
SPM279
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free. Also available Unmodified.
Immunogen
Mucins isolated from ovarian cyst fluid were used as the immunogen for the Blood Group Lewis a antibody.
Specificity
Human Blood Group Antigen Lewis A
Applications
  • IHC - Paraffin (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a carbohydrate determinant of Gal 1-3 (Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. Optimal dilution of the Blood Group Lewis a antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Presentation
1X PBS
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/15/2022