Leptin antibody LS-C187760 is a biotin-conjugated rabbit polyclonal antibody to human Leptin. Validated for ELISA and WB.
(tested or 100% immunogen sequence identity)
Leptin antibody was raised against (PHP198).
This product recognizes human leptin, a 16KDa major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure. Secreted leptin associates with proteins within the bloodstream and is transported to the brain, where it inhibits or up-regulates the activity of neuropeptides such as neuropeptide Y (NPY) and alpha-melanocyte-stimulating hormone respectively. Leptin is a recognized marker of obesity, with a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.