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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LBR / Lamin B Receptor Antibody LS‑C482452
Lamin B Receptor antibody LS-C482452 is an unconjugated rabbit polyclonal antibody to Lamin B Receptor (LBR) from human and mouse. Validated for IHC and WB.
Catalog
Size
Price
LS-C482452-50
50 µl (1 mg/ml)
$255
LS-C482452-100
100 µl (1 mg/ml)
$295
LS-C482452-200
200 µl (1 mg/ml)
$375

Popular LBR / Lamin B Receptor Products

Anti-LBR antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5128 concentration 2.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin
Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bovine, Guinea pig, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry of Human ovarian cancer using LBR Polyclonal Antibody at dilution of 1:50.
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Lamin B Receptor antibody LS-C482452 is an unconjugated rabbit polyclonal antibody to Lamin B Receptor (LBR) from human and mouse. Validated for IHC and WB.
About LBR / Lamin B Receptor
LBR / Lamin B Receptor belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. Q14739 NM_002296 NP_002287.2

LBR Antibody, DHCR14B Antibody, Lamin B receptor Antibody, Lamin-B receptor Antibody, PHA Antibody, LMN2R Antibody


Specifications

Target
Human LBR / Lamin B Receptor
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:200)
  • Western blot (1:500 - 1:2000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant full length human Lamin B Receptor.
Specificity
Recognizes endogenous levels of Lamin B Receptor protein.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only.

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Images

Immunohistochemistry

Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

Western blot

Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.
Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.

Immunohistochemistry

Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

Western blot

Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.
Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.

Immunohistochemistry

Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

Western blot

Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.
Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.

Immunohistochemistry

Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

Western blot

Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.
Western blot analysis of Lamin B Receptor expression in K562 (A); HT29 (B); mouse spleen (C); mouse lung (D) whole cell lysates.

Requested From: United States
Date Requested: 9/25/2018

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