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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LBR / Lamin B Receptor Antibody (aa503‑552, FITC) LS‑C447423
Lamin B Receptor antibody LS-C447423 is an FITC-conjugated rabbit polyclonal antibody to Lamin B Receptor (LBR) from human, bovine, chimpanzee and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C447423-100
100 µl (1 mg/ml)
Unavailable

Popular LBR / Lamin B Receptor Products

Anti-LBR antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5128 concentration 2.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin
Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bovine, Guinea pig, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry of Human ovarian cancer using LBR Polyclonal Antibody at dilution of 1:50.
Species: Human
Applications: IHC, Western blot, ELISA
Immunohistochemical analysis of Lamin B Receptor staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Lamin B Receptor antibody LS-C447423 is an FITC-conjugated rabbit polyclonal antibody to Lamin B Receptor (LBR) from human, bovine, chimpanzee and other species. Validated for IHC and WB.
About LBR / Lamin B Receptor
LBR / Lamin B Receptor belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. Q14739 NM_002296 NP_002287.2

LBR Antibody, DHCR14B Antibody, Lamin B receptor Antibody, Lamin-B receptor Antibody, PHA Antibody, LMN2R Antibody


Specifications

Target
Human LBR / Lamin B Receptor
Host
Rabbit
Reactivity
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Bovine, Guinea pig, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Dog, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Fluorescein. Also available Unconjugated or conjugated with Biotin, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide located between aa503-552 of human LBR (Q14739, NP_002287). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Panda (100%); Mouse, Rat, Hamster, Dog, Bat, Rabbit, Horse (92%); Sea squirt (91%); Elephant, Bovine, Guinea pig, Platypus (85%); Opossum (84%); Stickleback (83%).
Epitope
aa503-552
Specificity
Human LBR
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS.
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Immunohistochemistry

Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-LBR / Lamin B Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8099 dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
LBR antibody LS-B8099 Western blot of RPMI-8226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 7/18/2018

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