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| Catalog Number | Size | Price |
|---|---|---|
| LS-C357951-20 | 20 µg (0.2 mg/ml) | $371 |
| LS-C357951-100 | 100 µg (0.2 mg/ml) | $574 |
Monoclonal Mouse anti‑Human Ku70+Ku80 / XRCC6+XRCC5 Antibody (clone KU729, IHC, IF) LS‑C357951
Monoclonal Mouse anti‑Human Ku70+Ku80 / XRCC6+XRCC5 Antibody (clone KU729, IHC, IF) LS‑C357951
Antibody:
Ku70+Ku80 / XRCC6+XRCC5 Mouse anti-Human Monoclonal (KU729) Antibody
Application:
IHC, IHC-P, ICC, IF, IP, Flo
Reactivity:
Human, Primate
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
Ku70+Ku80 / XRCC6+XRCC5 Mouse anti-Human Monoclonal (KU729) Antibody
Application:
IHC, IHC-P, ICC, IF, IP, Flo
Reactivity:
Human, Primate
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
XRCC6+XRCC5 antibody LS-C357951 is an unconjugated mouse monoclonal antibody to XRCC6+XRCC5 (Ku70+Ku80) from human. It is reactive with human and primate. Validated for Flow, ICC, IF, IHC and IP.
Host
Mouse
Reactivity
Human, Primate
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat, Chicken
Clonality
IgG1,k
Monoclonal
Clone
KU729
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified.
Also available Azide-free, BSA-free.
Immunogen
Nuclear extract of human HL-60 cells.
Specificity
Human Ku70+Ku80 / XRCC6+XRCC5
Applications
- IHC
- IHC - Paraffin (0.5 - 1 µg/ml)
- ICC (0.25 - 0.5 µg/ml)
- Immunofluorescence (0.5 - 1 µg/ml)
- Immunoprecipitation
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
This antibody recognizes a dimer of two proteins of 70kDa (Ku70) and ~80kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Immunocytochemistry (Acetone-fixed cells) : 0.25-0.5ug/ml for 30 minutes at RT.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot
Species:
Human, Primate
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Source:
Insect
Tag:
His,N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
