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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KMT2A / MLL Antibody (AP)

MLL antibody LS-C509935 is an AP-conjugated mouse monoclonal antibody to MLL (KMT2A) from human and mouse. Validated for IP and WB.
100 µl
MLL antibody LS-C509935 is an AP-conjugated mouse monoclonal antibody to MLL (KMT2A) from human and mouse. Validated for IP and WB.
Human KMT2A / MLL
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Alkaline Phosphatase. Also available Unconjugated or conjugated with APC, Biotin, FITC, HRP, PE.
Protein G purified
  • Western blot
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
KMT2A / MLL antibody was raised against mBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL).
Recognizes the C-terminal proteolytic fragment of human MLL (MLLC), Mr ~180kD. Species cross-reactivity: Human and mouse.
PBS, pH 7.2, No preservatives added
Store at 4°C.
For research use only.
About KMT2A / MLL
Q03164 NM_005933 NP_005924.2

Popular KMT2A / MLL Products

WB Analysis: Samples: Nuclear extract (50 ug for WT and KO; 10 ug for EF, EN and EC) from 293T cells that were transfected with MLL1 C-terminal 180 kD fragment (EC), 293T cells transfected with N-terminally truncated MLL1 fragment (EN; N300-tr), 293T cells transfected with MLL1 N-terminal 300 kD fragment (EF), MLL1 +/+ mouse embryonic stem cells (WT), and MLL1 -/- embryonic stem cells (KO). Antibody used at the indicated concentrations. Detection: One second exposure with chemiluminescence.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species: Human, Mouse
Applications: Western blot, Immunoprecipitation
Detection of Human C-terminal 180 kDa Fragment of MLL1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from K562 (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-MLL1 antibody used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. The c-terminal 180 kDa Fragment of MLL1 was also immunoprecipitated by a prior lot of this antibody. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).
Species: Human, Mouse
Applications: Western blot, Immunoprecipitation, Chromatin Immunoprecipitation, Proximity Ligation Assay
Anti-MLL antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human
Applications: IHC, IHC - Paraffin, Flow Cytometry

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Requested From: United States
Date Requested: 1/23/2019
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