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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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KMT2A / MLL Antibody (aa3084‑3959, clone 4H354) LS‑C16577

Antibody

KMT2A / MLL Antibody (aa3084‑3959, clone 4H354) LS‑C16577

Antibody:
Mouse Monoclonal to Human KMT2A / MLL
Application:
WB, IP
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$785 
LS-C16577-200
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human KMT2A / MLL
Application:
WB, IP
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
MLL antibody LS-C16577 is an unconjugated mouse monoclonal antibody to MLL (KMT2A) from human and mouse. Validated for IP and WB.
Target
Human KMT2A / MLL
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
4H354
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (0.1 - 1 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Immunogen
KMT2A / MLL antibody was raised against mBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL).
Epitope
aa3084-3959
Specificity
Recognizes the C-terminal proteolytic fragment of human MLL (MLLC), Mr ~180kD. Species cross-reactivity: Human and mouse.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: Reported by an independent laboratory to immunoprecipitate MLLC from nuclear extracts. The N-terminal fragment, MLLN (300kD), is also co-immunoprecipitated by this antibody.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KMT2A / MLL
Q03164 NM_005933 NP_005924.2

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Requested From: United States
Date Requested: 7/24/2019
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