Rat KLRB1 / CD161

Mouse

Rat (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

10/78

Unconjugated

Protein G purified

Preservative Free. Also available Unmodified.

Purified splenic NK cells from the LEW rat strain.

Recognizes the rat Killer cell lectin-like receptor subfamily B protein, also known as NKR-PI or CD161. CD161 is a 233 amino acid ~60 kD type II single pass protein containing a single domain. CD161 is expressed on rat NK cells and T cell subpopulations. CD161 exists in 2 forms NKR-PIa and NKR-PIb, clone 10/78 Ârecognizes both forms of CD161. Clone 10/78 competes with another anti CD161 clone, 3.2.3 for binding to antigen. Has been successfully employed for the in vivo depletion of rat NK cells in an experimental obesity model.

• IHC - Frozen
• Western blot
• Immunoprecipitation
• Flow Cytometry (1:50 - 1:100)
• Radioimmunoassay

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 in 100 ul. Method sheets are available on request.

PBS

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q12918 NCBI: NM_002258 NP_002249.1