Krueppel-like factor family members are involved in growth regulation and a wide range of developmental processes. KLF4 is highly expressed in epithelial tissues including skin and stomach/intestine. Studies have shown that KLF4 can function as both an oncogene, upregulating hSSC, and a tumor suppressor, down-regulating colorectal cancer. KLF4 is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Store at -20°C. Avoid freeze-thaw cycles.
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