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KCNN2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants.

Gene Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Family/Subfamily: Ion Channel , Potassium channel - calcium-activated
Synonyms: KCNN2, HSK2, KCa2.2, Sk2, SKCA2, SKCa 2
Target Sequences: NM_021614 NP_067627.2 Q9H2S1

Publications (2)

1
Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium. Kim SH, Kim BG, Kim JY, Roh KJ, Suh MJ, Jung J, Moon IS, Moon SK, Choi JY. Scientific reports. 2015 5:18110. (IHC; Human) [Full Text Article] [PubMed:26655723] [PMC:PMC4677336] Related Antibodies: LS-A9578.
2
Heterogeneous upregulation of apamin-sensitive potassium currents in failing human ventricles. Chang PC, Turker I, Lopshire JC, Masroor S, Nguyen BL, Tao W, Rubart M, Chen PS, Chen Z, Ai T. Journal of the American Heart Association. 2013 2:e004713. (WB; Human) [Full Text Article] [PubMed:23525437] Related Antibodies: LS-B4408.

☰ Filters
Antibodies (14)
Proteins (4)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (14)
Sandwich (1)
KCNN2 (19)
Human (14)
Mouse (10)
Rat (10)
Bat (3)
Bovine (6)
Chicken (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (6)
Horse (6)
Monkey (7)
Orangutan (3)
Pig (6)
Rabbit (6)
IHC (5)
IHC-P (2)
WB (11)
ELISA (2)
IF (1)
Peptide-ELISA (2)
rabbit (12)
goat (1)
rabbit-new zealand white (1)
Product Group
IHCPlus (2)
IgG (11)
polyclonal pc (14)
96-Well Strip Plate (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (8)
aa443-492 (4)
aa72-121 (4)
C-Terminus (1)
aa545-557 (1)
No (17)
Yes (2)
Tissue Homogenates (1)
Myc-DDK (Flag) (4)
Human (2)
293T Cells (2)
HEK 293 Cells (2)
KCNN2 Antibody - Anti-KCNN2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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KCNN2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
KCNN2 Antibody - Anti-KCNN2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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KCNN2 Goat anti-Human Polyclonal (aa545-557) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
KCNN2 Antibody - Lane: Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human, Monkey
WB
Unconjugated
100 µl/$424
KCNN2 Antibody - Lane: Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
KCNN2 Antibody - Lane: Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
KCNN2 Antibody - Lane: Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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KCNN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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KCNN2 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
KCNN2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using KCNN2 Polyclonal Antibody at dilution of 1:30(×200)
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KCNN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNN2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using KCNN2 Polyclonal Antibody at dilution of 1:65(×200)
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KCNN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNN2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa443-492) Antibody
Rat, Human, Monkey
WB
Unconjugated
100 µl/$397
KCNN2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa443-492) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$442
KCNN2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa443-492) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$442
KCNN2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN2 Rabbit anti-Human Polyclonal (aa443-492) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$442
KCNN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
63.6 kDa
20 µg/$215
KCNN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.2 kDa
20 µg/$150
KCNN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.2 kDa
100 µg/$494
KCNN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
63.6 kDa
100 µg/$710
KCNN2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$902
Viewing 1-19 of 19 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).