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KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.

Gene Name: potassium large conductance calcium-activated channel, subfamily M beta member 3
Family/Subfamily: Ion Channel , Potassium channel - calcium-activated
Synonyms: KCNMB3, BK channel subunit beta-3, BK beta 3, BKBETA3, HKCNMB3, Maxi K beta 3, Maxi K channel subunit beta-3, K(VCA)beta-3, KCNMBL, Slo-beta-3, SLOBETA3, HBETA3
Target Sequences: NM_014407 NP_055222.3 Q9NPA1

☰ Filters
Proteins (12)
Antibodies (11)
Over-Expression Lysate (10)
Primary (11)
Recombinant (2)
KCNMB3 (23)
Human (11)
Mouse (2)
Rat (1)
IHC (4)
IHC-P (2)
WB (9)
ELISA (3)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (9)
mouse (2)
Product Group
IHCPlus (2)
IgG (2)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (9)
2C12 (1)
S40B-18 (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (8)
C-Terminus (5)
Internal (1)
aa1-49 (1)
aa160-173 (1)
No (23)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (10)
Human (7)
293T Cells (5)
E. coli (1)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (1)
KCNMB3 Antibody - Anti-KCNMB3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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KCNMB3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
KCNMB3 Antibody - Anti-KCNMB3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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KCNMB3 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
KCNMB3 Antibody - Lysate of COS cells transiently-transfected with BK Beta3a plasmid and probed
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KCNMB3 Mouse anti-Human Monoclonal (aa1-49) (S40B-18) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100 µg/$516
KCNMB3 Antibody - Immunohistochemistry of paraffin-embedded Human brain using KCNMB3 Polyclonal Antibody at dilution of 1:40.
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KCNMB3 Rabbit anti-Human Polyclonal (aa160-173) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNMB3 Antibody - Detection limit for recombinant GST tagged KCNMB3 is 1 ng/ml as a capture antibody.
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KCNMB3 Mouse anti-Human Monoclonal (2C12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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KCNMB3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
KCNMB3 Antibody - Western blot analysis of KCNMB3 using A549 whole cells lysates
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KCNMB3 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KCNMB3 Antibody - KCNMB3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNMB3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
KCNMB3 Antibody - KCNMB3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNMB3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
KCNMB3 Antibody - KCNMB3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNMB3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
KCNMB3 Antibody - KCNMB3 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNMB3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
KCNMB3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
19.3 kDa
20 µg/$150
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.4 kDa
20 µg/$150
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.2 kDa
20 µg/$150
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
28.9 kDa
20 µg/$150
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
30.9 kDa
20 µg/$150
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.2 kDa
100 µg/$494
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.9 kDa
100 µg/$494
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
30.9 kDa
100 µg/$494
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
19.3 kDa
100 µg/$494
KCNMB3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.4 kDa
100 µg/$494
KCNMB3 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-23 of 23 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).