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JTB / PAR

jumping translocation breakpoint

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 By similarity. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

Gene Name: jumping translocation breakpoint
Synonyms: JTB, HSPC222, HJT, PAR protein, Protein JTB, PAR, HJTB
Target Sequences: NM_006694 NP_006685.1 O76095

☰ Filters
Antibodies (14)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (14)
Recombinant (4)
Sandwich (1)
JTB / PAR (21)
Human (15)
Rat (1)
IHC (1)
WB (14)
ELISA (9)
IF (1)
Peptide-ELISA (3)
rabbit (8)
mouse (6)
IgG (6)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (8)
96-Well Strip Plate (1)
APC Conjugated (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (9)
20-100 aa, N-terminal (1)
aa10-59 (1)
aa16-99 (1)
aa40-89 (1)
No (21)
Cell Lysates (1)
Tissue Homogenates (1)
6His-SUMO, N-terminus (1)
Fc (1)
GST (1)
His (1)
Myc-DDK (Flag) (2)
Brugia malayi (1)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Human Cells (1)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (1)
JTB / PAR Antibody
Select
JTB / PAR Rabbit anti-Human Polyclonal (aa16-99) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
JTB / PAR Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
JTB / PAR Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
JTB / PAR Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
JTB / PAR Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
JTB / PAR Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
JTB / PAR Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
JTB / PAR Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
JTB / PAR Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
JTB / PAR Antibody - Western blot of JTB antibody
Select
JTB / PAR Rabbit anti-Human Polyclonal (20-100 aa, N-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
JTB / PAR Antibody - Western blot analysis of extracts from K562 cells, using JTB antibody.
Select
JTB / PAR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
JTB / PAR Rabbit anti-Human Polyclonal (aa10-59) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
JTB / PAR Antibody - Western blot analysis of the lysates from HUVECcells using JTB antibody.
Select
JTB / PAR Rabbit anti-Human Polyclonal (aa40-89) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
JTB / PAR Antibody
Select
JTB / PAR Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
JTB / PAR Antibody - Western blot analysis of extracts of various cell lines, using JTB antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Select
JTB / PAR Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
JTB / PAR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
JTB / PAR Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
34.7 kDa
100 µg/$843
JTB / PAR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.2 kDa
20 µg/$150
JTB / PAR Protein - 12.5% SDS-PAGE of human JTB stained with Coomassie Blue
Select
Wheat Germ Extract
GST
41.8 kDa
10 µg/$479; 25 µg/$670
JTB / PAR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.2 kDa
100 µg/$494
JTB / PAR Protein
Select
E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
Viewing 1-21 of 21 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).