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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C152905-100 100 µg (1 mg/ml) $435 
Antibody

ITGB3 / Integrin Beta 3 / CD61 Antibody LS‑C152905

ITGB3 / Integrin Beta 3 / CD61 Antibody LS‑C152905

Antibody:
Mouse Monoclonal to Human ITGB3 / Integrin Beta 3 / CD61
Application:
ICC, IP, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$435 
LS-C152905-100
100 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human ITGB3 / Integrin Beta 3 / CD61
Application:
ICC, IP, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
CD61 antibody LS-C152905 is an unconjugated mouse monoclonal antibody to human CD61 (ITGB3 / Integrin Beta 3 ). Validated for Flow, Func, ICC and IP.
Target
Human ITGB3 / Integrin Beta 3 / CD61
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgM Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • ICC
  • Immunoprecipitation
  • Flow Cytometry
  • Functional Assay
Immunogen
Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2.
Specificity
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61. The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kD reduced and 90 kD unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The monocytoid cell line U937 is highly positive. (original paper claimed IgG2ak)
Usage
Immunoprecipitation. Immunocytochemistry (acetone fixation required). Flow cytometry. Inhibits platelet aggregation, 10 ug/ml. Optimal working dilutions must be determined by end user.
Presentation
0.02 M PB, pH 7.6, 0.25 M NaCl, 0.1% Sodium Azide
Storage
Store at 4°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGB3 / Integrin Beta 3 / CD61
P05106 NM_000212 NP_000203.2

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Requested From: United States
Date Requested: 11/20/2019