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ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV‑7, Low Endotoxin) LS‑C44881

Catalog Number Size Price
LS-C44881-0.5 0.5 mg $590 
Antibody

ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV‑7, Low Endotoxin) LS‑C44881

Antibody:
Rat Monoclonal to Mouse ITGAV/Integrin Alpha V/CD51
Application:
IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Low Endotoxin
Other formats:
Price
Catalog Number
$590 
LS-C44881-0.5
Toll Free North America
866-819-4732

Overview

Antibody:
Rat Monoclonal to Mouse ITGAV/Integrin Alpha V/CD51
Application:
IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Low Endotoxin
Other formats:

Specifications

Description
CD51 antibody LS-C44881 is an unconjugated rat monoclonal antibody to mouse CD51 (ITGAV / Integrin Alpha V). Validated for Flow and IP.
Target
Mouse ITGAV/Integrin Alpha V/CD51
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
RMV-7
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Low Endotoxin. Also available Unmodified.
Applications
  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:100)
  • (applications tested for the base form of this product only)
Immunogen
Cultured LAK cells from Balb/c mice
Specificity
Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS
Storage
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGAV/Integrin Alpha V/CD51
P06756 NM_002210 NP_002201.1

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Requested From: United States
Date Requested: 9/18/2019