CD11b antibody LS-C524127 is a biotin-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IHC and IP.
(tested or 100% immunogen sequence identity)
Also available conjugated with AP
ITGAM / CD11b antibody was raised against t cell enriched splenocytes from B10 mice.
Recognizes the mouse CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone 3H955.15 has been reported to block iC3b binding to its receptor.* Has been reported to as being suitable for use on plp fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue (4.