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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGAM / CD11b Antibody (Biotin) for IHC, IP, Flow LS-C524127

CD11b antibody LS-C524127 is a biotin-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IHC and IP.
Catalog
Size
Price
LS-C524127-100
100 µl
$560
Description
CD11b antibody LS-C524127 is a biotin-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IHC and IP.
Target
Mouse ITGAM / CD11b
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Biotin. Also available conjugated with AP, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • Immunoprecipitation
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ITGAM / CD11b antibody was raised against t cell enriched splenocytes from B10 mice.
Specificity
Recognizes the mouse CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone 3H955.15 has been reported to block iC3b binding to its receptor.* Has been reported to as being suitable for use on plp fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue (4.
Presentation
PBS, pH 7.2
Storage
Store at 4°C.
Restrictions
For research use only.
About ITGAM / CD11b
P11215 NM_000632 NP_000623.2

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Requested From: United States
Date Requested: 1/20/2019
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