Mouse ITGAL / CD11a
ITGAL | CD11A | Integrin alpha-L | LFA-1 alpha | LFA-1A | Integrin gene promoter | Alpha polypeptide) | CD11a antigen | LFA-1 | LFA1A
(tested or 100% immunogen sequence identity)
Recognizes murine CD11a, a ~170-180kD type I membrane glycoprotein, also known as the integrin alpha L subunit. CD11a is a member of the integrin family of adhesion molecules. CD11a is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes. Is reported to block the cytolytic activity of cytotoxic T cell lines.