Human ITGA4 / VLA-4 / CD49d
ITGA4 | 269C wild type | CD49D | IA4 | Integrin alpha-4 | Integrin alpha 4 | Integrin alpha-4 subunit | Integrin alpha-IV | VLA-4 | VLA-4 subunit alpha | CD49d antigen
(tested or 100% immunogen sequence identity)
HOON pre-B leukaemia cell line.
Recognizes CD49d, also known as integrin alpha 4 subunit, which associates with either integrin beta 1 (to form VLA-4) or beta 7. CD49d is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin. Clone 44H6 is reported to induce homotypic aggregation. XXX has not confirmed this work.