Human ITGA2B / CD41
ITGA2B | BDPLT2 | CD41B | GT | gp2B | Integrin alpha-IIb | ITGAB | GPIIb | HPA3 | Platelet-specific antigen BAK | CD41 | CD41 antigen | GPalpha IIb | GTA
(tested or 100% immunogen sequence identity)
Ion exchange chromatography
Human platelet plasma membrane
Recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone Recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.