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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IRF2 Antibody (aa52‑101, HRP) LS‑C481723
IRF2 antibody LS-C481723 is an HRP-conjugated rabbit polyclonal antibody to IRF2 from human, rat, bat and other species. Validated for WB.
Catalog
Size
Price
LS-C481723-100
100 µl (0.65 mg/ml)
$385

Popular IRF2 Products

Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Staining (2?g/ml) of Jurkat lysate (RIPA buffer, 30?g total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Species: Human, Monkey, Mouse, Rat, Dog, Hamster, Horse
Applications: Western blot
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Applications: Western blot
Immunoperoxidase of monoclonal antibody to IRF2 on formalin-fixed paraffin-embedded human leiomyosarcoma. [antibody concentration 3 ug/ml]
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Immunohistochemistry - Paraffin Image
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot

Product Description

IRF2 antibody LS-C481723 is an HRP-conjugated rabbit polyclonal antibody to IRF2 from human, rat, bat and other species. Validated for WB.
About IRF2
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. P14316 NM_002199 NP_002190.2

IRF2 Antibody, IRF-2 Antibody, Interferon regulatory factor 2 Antibody


Specifications

Target
Human IRF2
Host
Rabbit
Reactivity
Human, Orangutan, Gibbon, Monkey, Rat, Bat, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Mouse, Bovine, Sheep, Zebrafish (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
IRF2 antibody was raised against synthetic peptide located between aa52-101 of human IRF2 (P14316, NP_002190). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Rat, Hamster, Elephant, Dog, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%); Mouse, Sheep, Bovine (92%); Pike, Zebrafish (90%); Turkey, Chicken, Xenopus (85%).
Epitope
aa52-101
Specificity
Human IRF2
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
100 mM sodium phosphate, pH 7.6, 150 mM NaCl
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.

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Images

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 9/23/2018

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