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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IRF1 / MAR Antibody (aa251‑300) LS‑C116008
MAR antibody LS-C116008 is an unconjugated rabbit polyclonal antibody to MAR (IRF1) from mouse, rat and rabbit. Validated for WB.
Catalog
Size
Price
LS-C116008-50
50 µg
$365

Popular IRF1 / MAR Products

IRF1 / IRF-1 /MAR antibody. IHC(P): Human Intestinal Cancer Tissue.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Antibody
Species: Mouse, Human, Rat
Applications: Western blot
HepG2 cell lysate. Antibody concentration: 1.2 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Sheep
Applications: Western blot
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Species: Human, Monkey, Mouse, Rat, Dog, Pig
Applications: IHC, IHC - Paraffin, Western blot
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit, Sheep
Applications: Western blot

Product Description

MAR antibody LS-C116008 is an unconjugated rabbit polyclonal antibody to MAR (IRF1) from mouse, rat and rabbit. Validated for WB.
About IRF1 / MAR
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. P10914 NM_002198 NP_002189.1

IRF1 Antibody, Interferon regulatory factor 1 Antibody, IRF-1 Antibody, MAR Antibody


Specifications

Target
Mouse IRF1 / MAR
Host
Rabbit
Reactivity
Mouse, Rat, Rabbit (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
IRF1 / MAR antibody was raised against synthetic peptide located between aa251-300 of mouse Irf1 (P15314, NP_032416). Percent identity by BLAST analysis: Mouse, Rat (100%); Human, Gorilla, Gibbon, Baboon, Monkey (92%); Ferret, Sheep, Panda, Bovine (90%); Marmoset, Rabbit, Guinea pig, Armadillo (85%); Galago (84%).
Blocking Peptide
LS-E13232 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C116008. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa251-300
Specificity
Mouse IRF1
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
Lyophilized from PBS, 0.09% sodium azide, 2% sucrose
Reconstitution
Centrifuge the vial prior to opening. Reconstitute with sterile distilled water to a concentration of 1 mg/ml. Vortex and centrifuge again.
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Images

Western blot

IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IRF1 antibody LS-C116008 Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 9/23/2018

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