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ILT3 / LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
ILT3 / LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | LILRB4, CD85K, CD85k antigen, ILT-3, ILT3, LIR-5, LIR5, HM18 |
| Target Sequences: | NM_006847 NP_006838.3 Q8NHJ6 |
Publications (1)
1
NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures. Carrega P, Loiacono F, Di Carlo E, Scaramuccia A, Mora M, Conte R, Benelli R, Spaggiari GM, Cantoni C, Campana S, Bonaccorsi I, Morandi B, Truini M, Mingari MC, Moretta L, Ferlazzo G. Nature communications. 2015 6:8280. (WB; Human)
[Full Text Article]
[PubMed:26395069]
Related Antibodies: LS-C261904.
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ILT3 / LILRB4 Mouse anti-Human Monoclonal (Extracellular Domain) (293622) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$919
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
20 µl/$275; 100 µl/$389
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ILT3 / LILRB4 Rabbit anti-Mouse Polyclonal (aa24-206) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ILT3 / LILRB4 Mouse anti-Human Monoclonal (CF) Antibody
Human
Flo
CF Conjugated
100 Tests/$649
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ILT3 / LILRB4 Mouse anti-Human Monoclonal (Extracellular Domain) (293623) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$962
ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ILT3 / LILRB4 Mouse anti-Human Monoclonal (APC) (293623) Antibody
Human
Flo
APC Conjugated
100 Tests/$824
E. coli
His-T7
24.3 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$294; 100 µl/$360
ILT3 / LILRB4 Mouse anti-Human Monoclonal (ZM4.1) Antibody
Human
Flo
Unconjugated
100 µg/$483
ILT3 / LILRB4 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
Flo
Unconjugated, Preservative Free
100 µl/$412
ILT3 / LILRB4 Mouse anti-Human Monoclonal (PE) (293623) Antibody
Human
Flo
PE Conjugated
100 Tests/$771
ILT3 / LILRB4 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
IHC-P
Unconjugated, Preservative Free
100 µl/$412
ILT3 / LILRB4 Mouse anti-Human Monoclonal (APC) (05) Antibody
Human
Flo
APC Conjugated
25 Tests/$278; 100 Tests/$376
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