Mouse IL2RB / CD122

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

TM-BETA 1

Unconjugated

Protein G purified

Low Endotoxin. Also available Unmodified.

Cells from murine IL-2RB + transformant TART-mBeta.

Recognizes the murine CD122 cell surface glycoprotein, a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. XXX recommend the use of For this purpose.

• Immunoprecipitation
• Flow Cytometry (1:10 - 1:50)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PBS

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P14784 NCBI: NM_000878 NP_000869.1