IL24

interleukin 24

IL24 is a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Products

Antibodies (68)

ELISA Kits (27)

Proteins (14)

Type

Custom (3)

Over-Expression Lysate (2)

Primary (68)

Recombinant (12)

Sandwich (20)

Sandwich CLIA (4)

Target

IL24 (109)

Reactivity

Human (62)

Mouse (8)

Rat (23)

Chicken (1)

Chimpanzee (3)

Guinea pig (1)

Monkey (2)

Orangutan (3)

Rabbit (1)

Sheep (1)

Application

IHC (10)

IHC-P (1)

WB (59)

Flo (1)

ELISA (18)

Peptide-ELISA (2)

SDS-PAGE (2)

Host

rabbit (49)

mouse (19)

Product Group

IHCPlus (1)

Isotype

IgG (27)

IgG1 (10)

IgG2a,k (1)

IgG2b,k (8)

Clonality

monoclonal mc (20)

polyclonal pc (48)

Clone

101 (1)

2B5 (1)

OTI3C5 (2)

OTI4D1 (2)

OTI4E1 (2)

OTI4H4 (2)

OTI5C8 (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (3)

96-Well Strip Plate (22)

APC (3)

APC Conjugated (5)

Azide-free (1)

Biotin Conjugated (7)

Carrier-free (5)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (5)

Preservative Free (2)

Unconjugated (31)

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Epitope

aa52-206 (10)

aa29-183 (8)

aa51-206 (8)

aa139-168 (7)

C-Terminus (4)

131-180 aa, Internal (1)

aa100-150 (1)

aa142-206 (1)

Publications

No (108)

Yes (1)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (3)

Plasma (19)

Serum (19)

Tissue Homogenates (5)

Tag

GST (2)

GST, N-terminus (1)

His, C-Terminal (1)

His, N-Terminal (2)

His,C-terminus (1)

His-GST (1)

Human IgG1 Fc (1)

Mouse IgG1 Fc, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (12)

Rat (1)

Source

293T Cells (1)

CHO Cells (3)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (3)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (5)

Biologically Active

Biologically active (2)

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IHC-plus™ IL24 Antibody (aa100-150) LS-B113

(4.0) Rating

Antibody:

IL24 Rabbit anti-Human Polyclonal (aa100-150) Antibody

Reactivity:

Human, Monkey

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IL24 Antibody (clone 2B5) LS-C139063

Antibody:

IL24 Mouse anti-Human Monoclonal (2B5) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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Human IL24 Protein (Recombinant His, C-Terminal) - LS-G187

Source:

CHO Cells

Tag:

His, C-Terminal

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.9 kDa

Price:

5 µg/$268; 20 µg/$349

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Human IL24 Protein (Recombinant His, N-Terminal) (aa51-206) - LS-G14688

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

19.5 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human IL24 (Sandwich ELISA) ELISA Kit - LS-F5418

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.8 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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IL24 Antibody (clone 101, Preservative Free) LS-C819022

Antibody:

IL24 Rabbit anti-Human Monoclonal (Preservative Free) (101) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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IL24 Antibody (FITC) LS-C395506

Antibody:

IL24 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

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Human IL24 Protein (Recombinant His,C-terminus) (Met1-Leu207) - LS-G47159

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant human IL24 consists of 166 amino acids and has a predicted molecular mass of 19.5 kDa. As a result of different glycosylation, the apparent molecular mass of rhIL24 is approximately 35 kDa in SDS-PAGE under reducing conditions.

Price:

50 µg/$364; 1 mg/$2,003

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Human IL24 Protein (Recombinant GST, N-terminus) (aa58-167) - LS-G61708

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL24 Protein (Recombinant GST) (Full Length) - LS-G32450

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.51 kDa

Price:

10 µg/$479; 25 µg/$670

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Rat IL24 (CLIA) ELISA Kit - LS-F26455

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$1,034

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Human IL24 Protein (Recombinant His, N-Terminal) (GLy51-Leu206) - LS-G132799

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

18kDa

Price:

10 µg/$295; 50 µg/$530; 200 µg/$1,045; 100 µg/$847; 1 mg/$2,211; 500 µg/$1,728; 5 mg/$3,697; 2 mg/$2,402

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Human IL24 Protein (Recombinant Human IgG1 Fc) (aa53-207) - LS-G4026

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

25 µg/$491

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Human IL24 (Sandwich ELISA) ELISA Kit - LS-F644

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

63 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$618

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IL24 Antibody (aa52-206, clone OTI3C5) LS-C794893

Antibody:

IL24 Mouse anti-Human Monoclonal (aa52-206) (OTI3C5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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IL24 Antibody (aa52-206, clone OTI3C5, Carrier-free) LS-C792049

Antibody:

IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI3C5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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IL24 Antibody (aa52-206, clone OTI4H4) LS-C794929

Antibody:

IL24 Mouse anti-Human Monoclonal (aa52-206) (OTI4H4) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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IL24 Antibody (aa52-206, clone OTI4H4, Carrier-free) LS-C798688

Antibody:

IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI4H4) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

IL24 Antibody (aa52-206, clone OTI4E1) LS-C794891

Antibody:

IL24 Mouse anti-Human Monoclonal (aa52-206) (OTI4E1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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IL24 Antibody (aa52-206, clone OTI4E1, Carrier-free) LS-C792047

Antibody:

IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI4E1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

IL24 Antibody LS-C809588

Antibody:

IL24 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IL24 Antibody LS-C331744

Antibody:

IL24 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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IL24 Antibody LS-C830038

Antibody:

IL24 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IL24 Antibody LS-C666405

Antibody:

IL24 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

IL24 Antibody (aa139-168) LS-C322219

Antibody:

IL24 Rabbit anti-Human Polyclonal (aa139-168) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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