Mouse IL1A / IL-1 Alpha

Mouse

Mouse (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

Flo1

Unconjugated

Affinity purified

Preservative Free

Recombinant mouse IL-1 alpha.

Recognizes mouse interleukin-1 alpha (IL-1 alpha), a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily, secreted by activated macrophages and monocytes, which mediates a wide range of immune and inflammatory responses. IL-1 alpha and closely related IL-1 beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a. Clone Flo1 can be used in functional studies to neutralize the activity of 125pg/ml of recombinant mouse IL-1 alpha by 95%, as tested using mouse D10(N4)M T-helper cells.

• ELISA

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

PBS

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01583 NCBI: NM_000575 NP_000566.3