Mouse IL1A / IL-1 Alpha
IL1A | Hematopoietin-1 | IL-1 alpha | IL1 | IL1-ALPHA | IL1 Alpha | Interleukin-1 alpha | IL-1A | IL1F1 | Pro-interleukin-1-alpha | Preinterleukin 1 alpha | Interleukin 1, alpha
(tested or 100% immunogen sequence identity)
Recombinant mouse IL-1 alpha.
Recognizes mouse interleukin-1 alpha (IL-1 alpha), a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily, secreted by activated macrophages and monocytes, which mediates a wide range of immune and inflammatory responses. IL-1 alpha and closely related IL-1 beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a. Clone Flo1 can be used in functional studies to neutralize the activity of 125pg/ml of recombinant mouse IL-1 alpha by 95%, as tested using mouse D10(N4)M T-helper cells.