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IL17A
interleukin 17A
IL17A is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
| Gene Name: | interleukin 17A |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL17A, CTLA-8, CTLA8, Interleukin-17A, Interleukin 17A, IL-17, IL-17A, IL17 |
| Target Sequences: | NM_002190 NP_002181.1 Q16552 |
Publications (3)
1
Bilberry-Derived Anthocyanins Modulate Cytokine Expression in the Intestine of Patients with Ulcerative Colitis. Roth S, Spalinger MR, Gottier C, Biedermann L, Zeitz J, Lang S, Weber A, Rogler G, Scharl M. PloS one. 2016 11:e0154817. (IHC; Human)
[Full Text Article]
[PubMed:27152519]
[PMC:PMC4859486]
Related Antibodies: LS-B8323.
2
Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease. Sherrie J Divito, Anders T Aasebø, Tiago R Matos, Pei-Chen Hsieh, Matthew Collin, Christopher P Elco, John T O'Malley, Espen S Bækkevold, Henrik Reims, Tobias Gedde-Dahl, Michael Hagerstrom, Jude Hilaire, John W Lian, Edgar L Milford, Geraldine S Pinkus, Vincent T Ho, Robert J Soiffer, Haesook T Kim, Martin C Mihm, Jerome Ritz, Indira Guleria, Corey S Cutler, Rachael A Clark, Frode L Jahnsen, Thomas S Kupper. The Journal of clinical investigation. 2020 September;130:4624-4636. [Full Text Article]
[PubMed:32516138]
[PMC:PMC7456221]
Related Antibodies: LS-C104427.
3
Siramesine causes preferential apoptosis of mast cells in skin biopsies from psoriatic lesions. E Hagforsen, M Lampinen, A Paivandy, S Weström, H Velin, S Öberg, G Pejler, O Rollman. The British journal of dermatology. 2017 July;177:179-187. [Full Text Article]
[PubMed:28117878]
Related Antibodies: LS-B7397.
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Neuroscience
IL17A Mouse anti-Human Monoclonal (aa1-75) (4K5F6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
IL17A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
IL17A Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
IL17A Goat anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL17A Goat anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
IL17A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL17A Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL17A Rabbit anti-Rat Polyclonal (Biotin) Antibody
Mouse, Rat
ELISA, IHC, WB
Biotin Conjugated
100 µg/$552
IL17A Mouse anti-Human Monoclonal (3-36.2.7.3) Antibody
Human
ELISA
Unconjugated
200 µg/$541
IL17A Mouse anti-Human Monoclonal (PE) (41802) Antibody
Human
Flo
PE Conjugated
100 Tests/$872
IL17A Mouse anti-Human Monoclonal (PE) (BL168) Antibody
Human
Flo
PE Conjugated
20 Tests/$256; 100 Tests/$325; 200 Tests/$382
IL17A Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$872
Sandwich
96-Well Strip Plate
Hamster
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
IL17A Mouse anti-Human Monoclonal (aa25-155) Antibody
Human
ELISA
Unconjugated
100 µl/$445
IL17A Mouse anti-Human Monoclonal (3.41.2.6.1) Antibody
Human
ELISA
Unconjugated
200 µg/$541
IL17A Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo, IF, WB
Unconjugated
500 µg/$558
IL17A Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$567
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
IL17A Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$351
IL17A Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL17A Mouse anti-Human Monoclonal (Biotin) (4H1524.1) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
100 µg/$582
IL17A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µg/$552
IL17A Rabbit anti-Mouse Polyclonal (aa26-158) Antibody
Mouse
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL17A Mouse anti-Human Monoclonal (Preservative Free) (M237) Antibody
Human
Block, ELISA, Neut
Unconjugated, Preservative Free
200 µg/$398; 500 µg/$511
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