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IL12RB1 / CD212
interleukin 12 receptor, beta 1
IL12RB1 / CD212 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
| Gene Name: | interleukin 12 receptor, beta 1 |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL12RB1, CD212, IL-12R subunit beta-1, IL-12R-beta-1, IL12R, Interleukin-12 receptor, IL-12 receptor subunit beta-1, IL-12R-BETA1, IL-12RB1, CD212 antigen, IL-12 receptor beta component, IL12RB |
| Target Sequences: | NM_005535 NP_005526.1 P42701 |
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IL12RB1 / CD212
(71)
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(8)
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(8)
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(8)
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(2)
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(1)
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IL12RB1 / CD212 Rabbit anti-Human Polyclonal (211-260 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
IL12RB1 / CD212 Goat anti-Mouse Polyclonal (Extracellular Domain) (PE) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$811
HEK 293 Cells
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human IL12RB1 consists of 528 amino acids and predictes a molecular mass of 58.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhIL12RB1 is approximately 70 kDa due to glycosylation.
100 µg/$379; 1 mg/$1,952
E. coli
His-GST-S
46.5 kDa
10 µg/$290; 50 µg/$500; 100 µg/$797; 200 µg/$997; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
Insect Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
50 µg/$361; 250 µg/$985; 10 µg/$261
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
IL12RB1 / CD212 Goat anti-Human Polyclonal (aa451-463) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
IL12RB1 / CD212 Rabbit anti-Human Polyclonal (aa37-234) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511
IL12RB1 / CD212 Rabbit anti-Human Polyclonal (aa37-234) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
58.5 kDa
100 µg/$483
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
IL12RB1 / CD212 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL12RB1 / CD212 Rabbit anti-Mouse Polyclonal (aa197-348) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL12RB1 / CD212 Mouse anti-Human Monoclonal (aa33-283) (OTI1A6) Antibody
Human
WB
Unconjugated
100 µl/$434
IL12RB1 / CD212 Mouse anti-Human Monoclonal (aa33-283) (Carrier-free) (OTI1A6) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
IL12RB1 / CD212 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
IL12RB1 / CD212 Rabbit anti-Human Polyclonal (aa57-488) Antibody
Human
WB
Unconjugated
100 µl/$450
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